Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | CACNA2D1 | P54289 | 4/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 4/20 | 0.41 |
| ▸ | CACNB1 | Q02641 | 4/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 3/20 | 0.41 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4616075 | 0.84 | GAA (0.51) | ADRA1DCACNA2D1CACNA1BCACNB1CACNA1C | |
| SCHEMBL7282376 | 0.83 | SLC6A4 (0.49) | HTR1AHTR2AHTR7HTR6OPRD1 | |
| SCHEMBL7434817 | 0.82 | LMNA (0.51) | OPRM1OPRD1OPRK1OPRL1ALDH1A1 | |
| SCHEMBL7445756 | 0.80 | CES2 (0.46) | CACNA2D1CACNA1BCACNB1CACNA1COPRM1 | |
| SCHEMBL7434230 | 0.78 | P2RX7 (0.38) | CACNA2D1CACNA1BCACNB1HTR2ATRPM8 | |
| SCHEMBL7426489 | 0.76 | CHRM2 (0.38) | ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL7437442 | 0.75 | TSHR (0.45) | CACNA2D1CACNA1BCACNB1CACNA1CHTT | |
| SCHEMBL7440321 | 0.74 | GAA (0.49) | ALDH1A1MAPTHTT | |
| SCHEMBL7434643 | 0.74 | CES2 (0.38) | TRPM8ALDH1A1 | |
| SCHEMBL7435488 | 0.72 | CYP3A4 (0.36) | ALDH1A1HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |