Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6997599 | 0.72 | TRPA1 (0.46) | TRPA1CYP11B2MAOAMAOB | |
| SCHEMBL7500741 | 0.70 | MAOA (0.44) | TRPA1MAPTMAOAMAOB | |
| SCHEMBL7000747 | 0.68 | TRPA1 (0.42) | TRPA1 | |
| SCHEMBL11563083 | 0.66 | NOS3 (0.39) | TRPA1MAPT | |
| SCHEMBL3707900 | 0.64 | TRPA1 (0.46) | TRPA1CYP11B2MAOAMAOB | |
| SCHEMBL5026786 | 0.64 | TRPA1 (0.46) | TRPA1CYP11B2MAOAMAOB | |
| SCHEMBL3611132 | 0.63 | ACHE (0.49) | TRPA1CYP11B2MAOAMAOB | |
| SCHEMBL6046310 | 0.61 | MAOA (0.44) | MAPTMAOAMAOB | |
| SCHEMBL1651565 | 0.60 | TRPA1 (0.41) | TRPA1 | |
| SCHEMBL28188526 | 0.60 | TRPA1 (0.37) | TRPA1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4322346-A | 5H-2,3-Benzodiazepine derivatives | KOROSI JENO | 1982-03-30 | — | — | US | disclosed |