Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | THRB | P10828 | 3/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7292487 | 0.87 | KDM4E (0.45) | MAOAMAOBXDHALDH1A1KDM4E | |
| SCHEMBL7429204 | 0.81 | SPHK1 (0.41) | ALDH1A1THRBTHRAHPGD | |
| SCHEMBL7431600 | 0.80 | CHRM2 (0.37) | ALDH1A1KDM4EHPGDSMN1; SMN2CHRM2 | |
| SCHEMBL7435882 | 0.77 | THRB (0.36) | ALDH1A1KDM4ETHRBTHRALMNA | |
| SCHEMBL7435723 | 0.76 | CHRM2 (0.32) | LMNAGAASMN1; SMN2CHRM2CHRM1 | |
| SCHEMBL7437442 | 0.76 | TSHR (0.45) | LMNASMN1; SMN2CHRM2CHRM1 | |
| SCHEMBL7434817 | 0.74 | LMNA (0.51) | ALDH1A1LMNAGAA | |
| SCHEMBL7426489 | 0.74 | CHRM2 (0.38) | ALDH1A1LMNAGAASMN1; SMN2CHRM2 | |
| SCHEMBL7288309 | 0.73 | MAOA (0.48) | MAOAMAOBXDHALDH1A1THRB | |
| SCHEMBL7431638 | 0.73 | EPHX1 (0.55) | LMNACHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |