Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 9/20 | 0.41 |
| ▸ | SPHK2 | Q9NRA0 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.39 |
| ▸ | OXTR | P30559 | 1/20 | 0.39 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.39 |
| ▸ | RARB | P10826 | 1/20 | 0.38 |
| ▸ | PLK1 | P53350 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7279720 | 0.86 | OPRD1 (0.41) | SPHK1SPHK2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL7435882 | 0.83 | THRB (0.36) | ALDH1A1HSD17B10THRATHRB | |
| SCHEMBL7431638 | 0.81 | EPHX1 (0.55) | RARB | |
| SCHEMBL7438903 | 0.81 | MAOA (0.40) | ALDH1A1HPGDTHRATHRB | |
| SCHEMBL7435723 | 0.79 | CHRM2 (0.32) | — | |
| SCHEMBL7437442 | 0.79 | TSHR (0.45) | — | |
| SCHEMBL7426489 | 0.77 | CHRM2 (0.38) | ALDH1A1 | |
| SCHEMBL7434817 | 0.77 | LMNA (0.51) | ALDH1A1OPRL1 | |
| SCHEMBL7431600 | 0.75 | CHRM2 (0.37) | ALDH1A1HPGD | |
| SCHEMBL7439650 | 0.75 | CHRM2 (0.56) | ALDH1A1HPGDTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |