Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7432645 | 0.84 | ENPP2 (0.47) | POLBENPP2MEN1USP2GAA | |
| SCHEMBL7428792 | 0.81 | CYP2D6 (0.45) | POLBENPP2KMT2ANPSR1 | |
| SCHEMBL7428456 | 0.81 | PLA2G10 (0.45) | POLBENPP2NPSR1HSD17B2KDM4E | |
| SCHEMBL7435811 | 0.81 | ACHE (0.41) | ACHEPOLBENPP2MEN1USP2 | |
| SCHEMBL7426522 | 0.79 | MAPT (0.43) | ACHEPOLBENPP2MEN1USP2 | |
| SCHEMBL7440468 | 0.79 | POLB (0.37) | POLBMEN1USP2GAAMAPT | |
| SCHEMBL7445692 | 0.78 | ENPP2 (0.36) | ACHEPOLBENPP2MEN1KMT2A | |
| SCHEMBL7436003 | 0.77 | HDAC6 (0.42) | POLBENPP2MEN1USP2GAA | |
| SCHEMBL7440735 | 0.76 | L3MBTL1 (0.42) | ENPP2MEN1GAAKMT2AL3MBTL1 | |
| SCHEMBL7435831 | 0.75 | ACHE (0.40) | ACHEPOLBMEN1USP2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640594-A1 | Hydantoin derivative as metalloprotease inhibitor | FUJIREBIO INC. (JP) | 1995-03-01 | — | — | EP | disclosed |