Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7437102 | 0.88 | CA2 (0.33) | CA1CA2CA7CA9CA14 | |
| SCHEMBL7448384 | 0.88 | MMP8 (0.37) | LMNA | |
| SCHEMBL7445495 | 0.83 | USP2 (0.32) | CA1CA2CA9ALDH1A1LMNA | |
| SCHEMBL7433244 | 0.83 | F2 (0.34) | CA2 | |
| SCHEMBL7445682 | 0.81 | ITGB1 (0.31) | — | |
| SCHEMBL7433865 | 0.80 | ITGB1 (0.31) | ALDH1A1 | |
| SCHEMBL7429926 | 0.80 | CA12 (0.33) | CA1CA2CA9 | |
| SCHEMBL7442390 | 0.80 | CA1 (0.41) | AKR1C3CA1CA2CA7CA9 | |
| SCHEMBL7441733 | 0.79 | AKR1C3 (0.41) | AKR1C3CA1CA2CA7CA9 | |
| SCHEMBL7433114 | 0.79 | TBXA2R (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5814622-A | COMPOUND USEFUL AS TRYPSIN LIKE SERINE PROTEASE AS THROMBIN INHIBITORS | ADIR ET COMPAGNIE (FR) | 1998-09-29 | — | — | US | disclosed |