Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 5/20 | 0.32 |
| ▸ | SPHK1 | Q9NYA1 | 4/20 | 0.32 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.30 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.30 |
| ▸ | PLG | P00747 | 2/20 | 0.30 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.30 |
| ▸ | PLAT | P00750 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7448384 | 0.85 | MMP8 (0.37) | SPHK1PRSS1 | |
| SCHEMBL7437102 | 0.82 | CA2 (0.33) | CA12CA1CA2CA9SPHK1 | |
| SCHEMBL7433865 | 0.82 | ITGB1 (0.31) | ITGB1ITGA4 | |
| SCHEMBL7445682 | 0.80 | ITGB1 (0.31) | ITGB1ITGA4 | |
| SCHEMBL7442402 | 0.80 | AKR1C3 (0.39) | CA1CA2CA9 | |
| SCHEMBL7444716 | 0.79 | MME (0.37) | ITGB1ITGA4 | |
| SCHEMBL7445495 | 0.79 | USP2 (0.32) | CA12CA1CA2CA9F2 | |
| SCHEMBL7433244 | 0.79 | F2 (0.34) | CA2F2ITGB1ITGA4 | |
| SCHEMBL7433114 | 0.78 | TBXA2R (0.30) | — | |
| SCHEMBL7443545 | 0.77 | ALDH1A1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5814622-A | COMPOUND USEFUL AS TRYPSIN LIKE SERINE PROTEASE AS THROMBIN INHIBITORS | ADIR ET COMPAGNIE (FR) | 1998-09-29 | — | — | US | disclosed |