SCHEMBL7433865

SCHEMBL7433865

CC(C)(Cc1ccccc1)NC(=O)C1(C(=O)NC(CCCB(O)OS(=O)(=O)c2ccccc2)NC(=N)N)CCCC1

nearest known ligand 0.31

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ITGB1 P05556 5/20 0.31
ITGA4 P13612 5/20 0.31
ITGB7 P26010 4/20 0.31
ALDH1A1 P00352 2/20 0.30
CYP2D6 P10635 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2C9 P11712 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7448384 0.84 MMP8 (0.37)
SCHEMBL7445682 0.83 ITGB1 (0.31) ITGB1ITGA4
SCHEMBL7429926 0.82 CA12 (0.33) ITGB1ITGA4
SCHEMBL7437102 0.81 CA2 (0.33) ITGB1ITGA4ALDH1A1
SCHEMBL7445495 0.81 USP2 (0.32) ITGB1ITGA4ALDH1A1
SCHEMBL7444716 0.81 MME (0.37) ITGB1ITGA4
SCHEMBL7433244 0.81 F2 (0.34) ITGB1ITGA4
SCHEMBL7442402 0.80 AKR1C3 (0.39) ALDH1A1
SCHEMBL7433114 0.80 TBXA2R (0.30)
SCHEMBL7443545 0.79 ALDH1A1 (0.42) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5814622-A COMPOUND USEFUL AS TRYPSIN LIKE SERINE PROTEASE AS THROMBIN INHIBITORS ADIR ET COMPAGNIE (FR) 1998-09-29 US disclosed