Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 2/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 5/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.34 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.34 |
| ▸ | MME | P08473 | 2/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GGT1 | P19440 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7437102 | 0.92 | CA2 (0.33) | SPHK1MMP1MMP2MMP3 | |
| SCHEMBL7445495 | 0.89 | USP2 (0.32) | LMNAMMP2 | |
| SCHEMBL7442402 | 0.88 | AKR1C3 (0.39) | LMNA | |
| SCHEMBL7445682 | 0.87 | ITGB1 (0.31) | — | |
| SCHEMBL7433244 | 0.85 | F2 (0.34) | F10MMP1 | |
| SCHEMBL7429926 | 0.85 | CA12 (0.33) | SPHK1PRSS1 | |
| SCHEMBL7433114 | 0.84 | TBXA2R (0.30) | — | |
| SCHEMBL7433865 | 0.84 | ITGB1 (0.31) | — | |
| SCHEMBL7444716 | 0.82 | MME (0.37) | MMEMAPT | |
| SCHEMBL7443545 | 0.80 | ALDH1A1 (0.42) | EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5814622-A | COMPOUND USEFUL AS TRYPSIN LIKE SERINE PROTEASE AS THROMBIN INHIBITORS | ADIR ET COMPAGNIE (FR) | 1998-09-29 | — | — | US | disclosed |