Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | OXTR | P30559 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3563776 | 0.73 | GRIK1 (0.43) | KDM2BALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL7404006 | 0.71 | PDE4B (0.52) | KDM2BHIF1A | |
| SCHEMBL7355186 | 0.70 | GPR119 (0.54) | ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL8902641 | 0.69 | HIF1A (0.63) | ALDH1A1RAB9AHIF1AMEN1KMT2A | |
| SCHEMBL7402370 | 0.68 | PDE4B (0.52) | ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL7356525 | 0.67 | HIF1A (0.34) | KDM2BALDH1A1RAB9AHIF1AOXTR | |
| SCHEMBL3823895 | 0.67 | RAB9A (0.38) | KDM2BALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL8094956 | 0.67 | LIPG (0.38) | — | |
| SCHEMBL2588369 | 0.67 | ALDH1A1 (0.56) | ALDH1A1RAB9AMEN1KMT2AAKR1C3 | |
| SCHEMBL8665462 | 0.67 | OXTR (0.55) | ALDH1A1HIF1AOXTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0714299-A4 | — | — | 1996-07-10 | — | — | EP | disclosed |
| EP-0714299-A1 | BENZOXAZINONE AND BENZOPYRIMIDINONE PIPERIDINYL TOCOLYTIC OXYTOCIN RECEPTOR ANTAGONISTS | MERCK & CO. INC. (US) | 1996-06-05 | — | — | EP | disclosed |
| WO-1995002405-A1 | BENZOXAZINONE AND BENZOPYRIMIDINONE PIPERIDINYL TOCOLYTIC OXYTOCIN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1995-01-26 | — | — | WO | disclosed |