Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.43 |
| ▸ | NHERF1 | O14745 | 3/20 | 0.42 |
| ▸ | PRKAB2 | O43741 | 3/20 | 0.40 |
| ▸ | PRKAG1 | P54619 | 3/20 | 0.40 |
| ▸ | PRKAA2 | P54646 | 3/20 | 0.40 |
| ▸ | PRKAA1 | Q13131 | 3/20 | 0.40 |
| ▸ | PRKAG3 | Q9UGI9 | 3/20 | 0.40 |
| ▸ | PRKAG2 | Q9UGJ0 | 3/20 | 0.40 |
| ▸ | PRKAB1 | Q9Y478 | 3/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7461248 | 0.88 | NHERF1 (0.51) | MAPTNR4A2NHERF1MEN1GABRP | |
| SCHEMBL474836 | 0.74 | ALDH1A1 (0.66) | MAPTNR4A2HDAC1MEN1GABRP | |
| SCHEMBL7461028 | 0.73 | NHERF1 (0.48) | NR4A2NHERF1GABRPGABRDGABRA1 | |
| Fluoride SCHEMBL31312793 | 0.73 | ALDH1A1 (0.64) | MAPTNR4A2HDAC1MEN1GABRP | |
| SCHEMBL2649037 | 0.71 | SPR (0.53) | MAPTNHERF1MEN1KMT2ALMNA | |
| SCHEMBL7464152 | 0.70 | NHERF1 (0.45) | NR4A2NHERF1GABRA1GABRB2KMT2A | |
| SCHEMBL11946603 | 0.70 | NHERF1 (0.71) | NR4A2NHERF1ROCK2ROCK1MEN1 | |
| SCHEMBL26204080 | 0.70 | NR4A2 (0.64) | MAPTNR4A2MEN1GABRA1GABRB1 | |
| SCHEMBL17423706 | 0.69 | PRKAB2 (0.52) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL27927329 | 0.69 | GABRA1 (0.52) | NR4A2PRKAB2PRKAG1PRKAA2PRKAA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1183252-A1 | NEW PHARMACEUTICALLY ACTIVE COMPOUNDS | AstraZeneca AB (SE) | 2002-03-06 | — | — | EP | disclosed |
| WO-2000071537-A1 | NEW PHARMACEUTICALLY ACTIVE COMPOUNDS | ASTRAZENECA AB (SE) | 2000-11-30 | — | — | WO | disclosed |