SCHEMBL7459472

SCHEMBL7459472

CCCCNC(=O)c1cccc(F)c1

nearest known ligand 0.79

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.79
NAMPT P43490 2/20 0.59
GAA P10253 2/20 0.58
NAAA Q02083 1/20 0.58
L3MBTL1 Q9Y468 1/20 0.56
HDAC1 Q13547 1/20 0.56
HDAC6 Q9UBN7 1/20 0.56
ALDH1A1 P00352 1/20 0.55
POLB P06746 1/20 0.55
MAPT P10636 1/20 0.54
TSHR P16473 1/20 0.54
HTT P42858 1/20 0.54
HPGD P15428 1/20 0.52
KDM4E B2RXH2 1/20 0.52
NPY1R P25929 1/20 0.52
RECQL P46063 1/20 0.52
NPY2R P49146 1/20 0.52
MLYCD O95822 1/20 0.51
TP53BP1 Q12888 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28929246 0.94 SMN1; SMN2 (0.69) SMN1; SMN2NAMPTGAANAAAL3MBTL1
SCHEMBL8350694 0.90 L3MBTL1 (0.69) SMN1; SMN2NAMPTGAAL3MBTL1HDAC1
SCHEMBL16117373 0.89 SMN1; SMN2 (1.00) SMN1; SMN2GAANAAAL3MBTL1HDAC1
SCHEMBL17141787 0.85 HDAC2 (0.70) SMN1; SMN2HDAC1HDAC6
SCHEMBL30914529 0.85 ALDH1A1 (0.64) SMN1; SMN2NAMPTGAAHDAC1HDAC6
SCHEMBL4595338 0.84 NAMPT (0.62) SMN1; SMN2NAMPTGAAHDAC1HDAC6
SCHEMBL31475190 0.83 HDAC1 (0.62) SMN1; SMN2GAAL3MBTL1HDAC1HDAC6
SCHEMBL7217481 0.83 HDAC1 (0.62) SMN1; SMN2GAAL3MBTL1HDAC1HDAC6
SCHEMBL7221137 0.83 NAMPT (0.61) SMN1; SMN2NAMPTGAAHDAC1HDAC6
SCHEMBL28855925 0.83 SMN1; SMN2 (0.77) SMN1; SMN2GAANAAAL3MBTL1HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260068882-A1 ARTHROPOD CONTROLLING COMPOSITION FIRMENICH & CIE (CH) 2026-03-12 US disclosed
CN-113873884-B Arthropod control composition 弗门尼舍有限公司 2024-06-14 CN disclosed
US-20220142157-A1 ARTHROPOD CONTROLLING COMPOSITION FIRMENICH SA (CH) 2022-05-12 US disclosed
US-20220142158-A1 ARTHROPOD CONTROL COMPOSITIONS FIRMENICH SA (CH) 2022-05-12 US disclosed
CN-113905612-A Arthropod control composition 弗门尼舍有限公司 2022-01-07 CN disclosed
CN-113873884-A Arthropod control composition 弗门尼舍有限公司 2021-12-31 CN disclosed
US-10768168-B2 Methods for identifying arthropod repellents and attractants, and compounds and compositions identified by such methods THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2020-09-08 US disclosed
EP-3409115-A2 METHODS FOR IDENTIFYING ARTHROPOD REPELLENTS, AND COMPOUNDS AND COMPOSITIONS IDENTIFIED BY SUCH METHODS The Regents of The University of California (US) 2018-12-05 EP disclosed
US-20180188235-A1 METHODS FOR IDENTIFYING ARTHROPOD REPELLENTS AND ATTRACTANTS, AND COMPOUNDS AND COMPOSITIONS IDENTIFIED BY SUCH METHODS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2018-07-05 US disclosed
US-9897592-B2 Methods for identifying arthropod repellents and attractants, and compounds and compositions identified by such methods THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2018-02-20 US disclosed
US-20170292944-A1 METHODS FOR IDENTIFYING ARTHROPOD REPELLENTS AND ATTRACTANTS, AND COMPOUNDS AND COMPOSITIONS IDENTIFIED BY SUCH METHODS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2017-10-12 US disclosed
EP-2972299-A2 METHODS FOR IDENTIFYING ARTHROPOD REPELLENTS AND ATTRACTANTS, AND COMPOUNDS AND COMPOSITIONS IDENTIFIED BY SUCH METHODS The Regents of The University of California (US) 2016-01-20 EP disclosed
US-20160003805-A1 METHODS FOR IDENTIFYING ARTHROPOD REPELLENTS AND ATTRACTANTS, AND COMPOUNDS AND COMPOSITIONS IDENTIFIED BY SUCH METHODS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2016-01-07 US disclosed
WO-2014144685-A2 METHODS FOR IDENTIFYING ARTHROPOD REPELLENTS AND ATTRACTANTS, AND COMPOUNDS AND COMPOSITIONS IDENTIFIED BY SUCH METHODS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2014-09-18 WO disclosed
EP-1175406-A1 IMIDAZOLINE DERIVATIVES AS ALPHA-1A ADRENOCEPTOR LIGANDS GLAXO GROUP LIMITED (GB) 2002-01-30 EP disclosed
WO-2000066563-A1 IMIDAZOLINE DERIVATIVES AS ALPHA-1A ADRENOCEPTOR LIGANDS GLAXO GROUP LIMITED (GB) 2000-11-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260068882-A1 ARTHROPOD CONTROLLING COMPOSITION CNOT9, MSL1, MT-CO2 SMN1; SMN2 2293/4885NAMPT 4833/4885GAA 4737/4885
US-10768168-B2 Methods for identifying arthropod repellents and attractants, and compounds and compositions identified by such methods TRPA1, ACHE, NCS1 SMN1; SMN2 1852/4885NAMPT 2103/4885GAA 3516/4885
US-20180188235-A1 METHODS FOR IDENTIFYING ARTHROPOD REPELLENTS AND ATTRACTANTS, AND COMPOUNDS AND COMPOSITIONS IDENTIFIED BY SUCH METHODS TRPA1, ACHE, NCS1 SMN1; SMN2 1852/4885NAMPT 2103/4885GAA 3516/4885
US-20170292944-A1 METHODS FOR IDENTIFYING ARTHROPOD REPELLENTS AND ATTRACTANTS, AND COMPOUNDS AND COMPOSITIONS IDENTIFIED BY SUCH METHODS TRPA1, ACHE, NCS1 SMN1; SMN2 1852/4885NAMPT 2103/4885GAA 3516/4885
US-20220142157-A1 ARTHROPOD CONTROLLING COMPOSITION AGO2, NOP2, FBL SMN1; SMN2 1753/4885NAMPT 2562/4885GAA 1982/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.