Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 8/20 | 0.36 |
| ▸ | LPAR5 | Q9H1C0 | 7/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.33 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.33 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL750906 | 0.90 | TP53 (0.39) | LPAR1LPAR5SRCTP53MAPT | |
| SCHEMBL751838 | 0.89 | ACHE (0.43) | SRCADORA2AADORA1NPSR1KMT2A | |
| SCHEMBL745530 | 0.89 | HDAC1 (0.41) | LPAR1LPAR5SRCRAB9AKMT2A | |
| SCHEMBL748197 | 0.89 | SRC (0.36) | LPAR1LPAR5SRCTP53MAPT | |
| SCHEMBL749993 | 0.87 | LPAR1 (0.39) | LPAR1LPAR5SRCMAPTRAB9A | |
| SCHEMBL747958 | 0.87 | TP53 (0.38) | LPAR1LPAR5SRCTP53MAPT | |
| SCHEMBL749665 | 0.87 | MAPT (0.42) | SRCTP53MAPTRAB9AKMT2A | |
| SCHEMBL747722 | 0.86 | ESRRG (0.41) | SRCTP53MAPTSLC13A5ALDH1A1 | |
| SCHEMBL751065 | 0.86 | SRC (0.38) | SRCTP53MAPTKMT2ASLC13A5 | |
| SCHEMBL748554 | 0.86 | LPAR1 (0.36) | LPAR1LPAR5TP53MAPTADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049493-B1 | COMPOUNDS SUITABLE AS MODULATORS OF HDL | CADILA HEALTHCARE LTD (IN) | 2012-03-21 | — | — | EP | claimed |