Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 8/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 8/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.37 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7089421 | 0.82 | PTGER2 (0.41) | HDAC1HDAC6TNFRSF1AMEN1KMT2A | |
| SCHEMBL27905635 | 0.78 | CES2 (0.47) | HCRTR1HCRTR2CES2CES1KMT2A | |
| SCHEMBL7085296 | 0.72 | PTGER2 (0.40) | TNFRSF1AMEN1RAB9AKMT2AKDM4E | |
| SCHEMBL27204316 | 0.70 | BAZ2B (0.53) | HCRTR1HCRTR2ARKDM4EHPGD | |
| SCHEMBL932848 | 0.68 | ALOX15 (0.53) | MEN1RAB9AKMT2AKDM4ENPC1 | |
| SCHEMBL15630555 | 0.68 | SRPK1 (0.50) | TNFRSF1AARMEN1RAB9AKMT2A | |
| SCHEMBL12302152 | 0.68 | HDAC1 (0.61) | HDAC1HDAC6CES2CES1RAB9A | |
| SCHEMBL6092124 | 0.68 | RAB9A (0.42) | HCRTR1HCRTR2RAB9AKDM4ENPC1 | |
| SCHEMBL6732189 | 0.68 | HPGDS (0.53) | HCRTR1HCRTR2MEN1KMT2AKDM4E | |
| SCHEMBL3559657 | 0.67 | ALDH1A1 (0.54) | HCRTR1HCRTR2ARMEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1211244-A2 | 4,5-substitued imidazolyl compounds for the treatment of inflammation | G.D. Searle & Co. (US) | 2002-06-05 | — | — | EP | disclosed |