Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | RAD52 | P43351 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7487377 | 0.89 | LMNA (0.40) | LMNAMAPTPOLBLIMK1SMN1; SMN2 | |
| SCHEMBL7489529 | 0.86 | ALDH1A1 (0.43) | LMNAMAPTPOLBLIMK1SMN1; SMN2 | |
| Dimethylamine SCHEMBL7490478 | 0.80 | POLB (0.44) | LMNAMAPTPOLBLIMK1SMN1; SMN2 | |
| Diethylamine SCHEMBL7488798 | 0.80 | MAPT (0.42) | LMNAMAPTPOLBLIMK1SMN1; SMN2 | |
| SCHEMBL7484725 | 0.68 | ABCC1 (0.40) | LMNAMAPTALDH1A1HPGDKDM4E | |
| SCHEMBL7485921 | 0.67 | SLC10A2 (0.48) | MAPTSMN1; SMN2ALDH1A1GAAKDM4E | |
| Diethylamine SCHEMBL7484722 | 0.65 | ABCG2 (0.51) | LMNAMAPTALDH1A1GAASLC10A2 | |
| SCHEMBL18456786 | 0.63 | PKM (0.45) | LMNAPOLBSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL1901332 | 0.63 | LMNA (0.61) | LMNAMAPTPOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL7671545 | 0.62 | MEN1 (0.55) | LMNAMAPTPOLBSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0791000-B1 | THIENOPYRIDINE OR THIENOPYRIMIDINE DERIVATIVES AND THEIR USE | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2002-10-02 | — | — | EP | disclosed |
| EP-0791000-A1 | THIENOPYRIDINE OR THIENOPYRIMIDINE DERIVATIVES AND THEIR USE | Takeda Chemical Industries, Ltd. (JP) | 1997-08-27 | — | — | EP | disclosed |
| WO-1996014319-A1 | THIENOPYRIDINE OR THIENOPYRIMIDINE DERIVATIVES AND THEIR USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-05-17 | — | — | WO | disclosed |