Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | DHFR | P00374 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diethylamine SCHEMBL7488798 | 0.92 | MAPT (0.42) | POLBMAPTLMNALIMK1MEN1 | |
| SCHEMBL7489529 | 0.81 | ALDH1A1 (0.43) | POLBMAPTLMNALIMK1MEN1 | |
| SCHEMBL7490464 | 0.80 | LMNA (0.41) | POLBMAPTLMNALIMK1KMT2A | |
| SCHEMBL7487377 | 0.78 | LMNA (0.40) | POLBMAPTLMNALIMK1MEN1 | |
| SCHEMBL1901332 | 0.72 | LMNA (0.61) | POLBMAPTLMNAMEN1KMT2A | |
| SCHEMBL10690098 | 0.71 | L3MBTL1 (0.51) | MAPTLMNAMEN1KMT2ADHFR | |
| SCHEMBL10686218 | 0.66 | DHFR (0.43) | MAPTMEN1KMT2ADHFRSMN1; SMN2 | |
| Diethylamine SCHEMBL8136070 | 0.64 | PDE4A (0.56) | MAPTDHFRSMN1; SMN2KDM4EL3MBTL1 | |
| SCHEMBL10682446 | 0.63 | DHFR (0.43) | MAPTLMNADHFRSMN1; SMN2KDM4E | |
| SCHEMBL19650460 | 0.63 | ADORA1 (0.56) | MAPTLMNAMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0791000-B1 | THIENOPYRIDINE OR THIENOPYRIMIDINE DERIVATIVES AND THEIR USE | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2002-10-02 | — | — | EP | disclosed |
| EP-0791000-A1 | THIENOPYRIDINE OR THIENOPYRIMIDINE DERIVATIVES AND THEIR USE | Takeda Chemical Industries, Ltd. (JP) | 1997-08-27 | — | — | EP | disclosed |
| WO-1996014319-A1 | THIENOPYRIDINE OR THIENOPYRIMIDINE DERIVATIVES AND THEIR USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-05-17 | — | — | WO | disclosed |