Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 3/20 | 0.37 |
| ▸ | HTR2C | P28335 | 3/20 | 0.37 |
| ▸ | HTR2B | P41595 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | BMP1 | P13497 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL745530 | 0.87 | HDAC1 (0.41) | BMP1 | |
| SCHEMBL748197 | 0.86 | SRC (0.36) | ALDH1A1SMN1; SMN2TP53MAPT | |
| SCHEMBL749647 | 0.86 | LMNA (0.39) | ALDH1A1SMN1; SMN2NPSR1MAPT | |
| SCHEMBL749300 | 0.86 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2HTR2AHTR2CHTR2B | |
| SCHEMBL750950 | 0.86 | SRC (0.36) | ALDH1A1SMN1; SMN2TP53MAPTTSHR | |
| SCHEMBL750133 | 0.86 | SRC (0.36) | SLC6A4HTR2ATP53MAPT | |
| SCHEMBL747722 | 0.86 | ESRRG (0.41) | ALDH1A1SMN1; SMN2TP53MAPT | |
| SCHEMBL750906 | 0.86 | TP53 (0.39) | SMN1; SMN2TP53MAPT | |
| Hydrochloric Acid SCHEMBL751875 | 0.86 | SRC (0.36) | ALDH1A1SMN1; SMN2TP53MAPTTSHR | |
| SCHEMBL749993 | 0.85 | LPAR1 (0.39) | ALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049493-B1 | COMPOUNDS SUITABLE AS MODULATORS OF HDL | CADILA HEALTHCARE LTD (IN) | 2012-03-21 | — | — | EP | claimed |