Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Cromolyn. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 known ✓ | Q9Y271 | 2/20 | 0.45 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 1.00 |
| ▸ | MEN1 | O00255 | 2/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 2/20 | 1.00 |
| ▸ | HIF1A | Q16665 | 1/20 | 1.00 |
| ▸ | LMNA | P02545 | 1/20 | 0.77 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.77 |
| ▸ | ABCG2 | Q9UNQ0 | 9/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.46 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.42 |
| ▸ | NMT2 | O60551 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.42 |
| ▸ | NMT1 | P30419 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cromolyn SCHEMBL29382339 | 1.00 | GPR35 (1.00) | GPR35MEN1KMT2AHIF1ALMNA | |
| Cromolyn SCHEMBL5060996 | 1.00 | GPR35 (1.00) | GPR35MEN1KMT2AHIF1ALMNA | |
| Cromolyn SCHEMBL29381782 | 1.00 | GPR35 (1.00) | GPR35MEN1KMT2AHIF1ALMNA | |
| Cromolyn SCHEMBL28105727 | 0.99 | GPR35 (0.98) | GPR35MEN1KMT2AHIF1ALMNA | |
| SCHEMBL11829448 | 0.93 | GPR35 (0.87) | GPR35MEN1KMT2AHIF1ALMNA | |
| SCHEMBL11833752 | 0.91 | GPR35 (0.83) | GPR35MEN1KMT2AHIF1ALMNA | |
| SCHEMBL11832978 | 0.91 | GPR35 (0.83) | GPR35MEN1KMT2AHIF1ALMNA | |
| SCHEMBL11835364 | 0.90 | GPR35 (0.82) | GPR35MEN1KMT2AHIF1ALMNA | |
| SCHEMBL11840633 | 0.90 | GPR35 (0.82) | GPR35MEN1KMT2AHIF1ALMNA | |
| SCHEMBL11841373 | 0.90 | GPR35 (0.82) | GPR35MEN1KMT2AHIF1ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 31091 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4747263-A1 | LIPID NANOPARTICLES AND USES THEREOF | University of Connecticut (US) | 2026-05-27 | — | — | EP | claimed |
| CN-117760980-B | Glucose detection method based on lyotropic liquid crystal liquid drops | 南京邮电大学 | 2026-05-15 | — | — | CN | claimed |
| US-12616803-B2 | Apparatus for dispensing inhalant medicament | METOPI PHARMACEUTICALS, INC. (US) | 2026-05-05 | — | — | US | claimed |
| WO-2026090557-A1 | SYSTEMS AND METHODS FOR PROCESSING ISM AND MCAS CLINICAL TRIAL DATA | TELIOS PHARMA INC. (US) | 2026-04-30 | — | — | WO | claimed |
| US-20260108514-A1 | METHOD OF INHIBITING EPITHELIAL-MESENCHYMAL TRANSITION AND CANCER METASTASIS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2026-04-23 | — | — | US | claimed |
| US-12605471-B2 | Cromolyn derivatives and related methods of imaging and treatment | THE GENERAL HOSPITAL CORPORATION (US) | 2026-04-21 | — | — | US | claimed |
| US-12599555-B2 | Formulation | HEWLETT HEALTHCARE LIMITED (GB) | 2026-04-14 | — | — | US | claimed |
| US-20260076872-A1 | POLYMER VIALS WITH SUBSTANTIALLY FLAT BOTTOMS AND INJECTION STRETCH BLOW MOLDING METHODS FOR MAKING THE SAME | SIO2 MEDICAL PRODUCTS LLC (US) | 2026-03-19 | — | — | US | claimed |
| EP-4687912-A1 | GENOTYPE-SPECIFIC METHODS AND SYSTEMS FOR TREATMENT OF NEURODEGENERATIVE DISEASE | Phenonet, Inc. (US) | 2026-02-11 | — | — | EP | claimed |
| US-12545948-B2 | Identification of novel loci in asthma and methods of use thereof for the diagnosis and treatment of asthma | THE CHILDREN'S HOSPITAL OF PHILADELPHIA (US) | 2026-02-10 | — | — | US | claimed |
| EP-0072046-A1 | Inhalation drugs, methods for their production and pharmaceutical formulations containing them | FISONS plc (GB) | 1983-02-16 | — | — | EP | claimed |
| EP-0051207-A1 | A pharmaceutical mixture containing sodium cromoglycate and a method of making the mixture | FISONS plc (GB) | 1982-05-12 | — | — | EP | claimed |
| US-4294829-A | Powdery pharmaceutical composition and powdery preparation for application to the nasal mucosa, and method for administration thereof | TEIJIN LIMITED (JP) | 1981-10-13 | — | — | US | claimed |
| EP-0036145-A1 | An orally administered drug form comprising a polar bioactive agent and an adjuvant | INTERx RESEARCH CORPORATION (US) | 1981-09-23 | — | — | EP | claimed |
| US-4269835-A | Nasal composition for relieving nasal distress | WHITTLE BARRY J | 1981-05-26 | — | — | US | claimed |
| EP-0023359-A2 | Powdery pharmaceutical composition and powdery preparation for application to the nasal mucosa, and method for administration thereof | TEIJIN LIMITED (JP) | 1981-02-04 | — | — | EP | claimed |
| US-4211777-A | GASTROINTESTINAL DISORDERS | FISONS LIMITED (GB) | 1980-07-08 | — | — | US | claimed |
| US-4192860-A | Methods for treating disease conditions | FISONS LIMITED (GB) | 1980-03-11 | — | — | US | claimed |
| US-4192886-A | Methods for treating gastrointestinal disease | FISONS LIMITED (GB) | 1980-03-11 | — | — | US | claimed |
| US-4161516-A | PELLET OR GRANULAR, ADAPTED TO BE FLUIDIZE AND USED AS INHALANT | FISONS LIMITED (GB) | 1979-07-17 | — | — | US | claimed |