SCHEMBL750073

SCHEMBL750073

O=S(=O)(Cl)Cc1ccc(F)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.44
IDO1 P14902 2/20 0.42
LOXL2 Q9Y4K0 1/20 0.42
TAAR1 Q96RJ0 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
EGFR P00533 2/20 0.39
ERBB2 P04626 2/20 0.39
USP2 O75604 1/20 0.38
LMNA P02545 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
FAAH O00519 1/20 0.38
PRSS1 P07477 1/20 0.38
PRSS2 P07478 1/20 0.38
ELANE P08246 1/20 0.38
PRTN3 P24158 1/20 0.38
PRSS3 P35030 1/20 0.38
AGXT P21549 1/20 0.38
CA1 P00915 2/20 0.38
CA2 P00918 2/20 0.38
CA9 Q16790 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7243419 0.87 CA2 (0.40) KMT2AL3MBTL1FAAHPRSS1PRSS2
SCHEMBL6964204 0.81 FAAH (0.38) KMT2AL3MBTL1FAAHPRSS1PRSS2
SCHEMBL422010 0.80 USP2 (0.51) KMT2AIDO1LOXL2TAAR1L3MBTL1
SCHEMBL925715 0.78 KMT2A (0.50) KMT2AIDO1TAAR1L3MBTL1EGFR
SCHEMBL9421733 0.78 FAAH (0.62) KMT2AIDO1LOXL2TAAR1L3MBTL1
SCHEMBL29221410 0.78 CA2 (0.41) KMT2AL3MBTL1FAAHPRSS1PRSS2
SCHEMBL66512 0.77 APLNR (0.50) IDO1TAAR1CA1CA2CA12
SCHEMBL777188 0.76 KMT2A (0.44) KMT2AIDO1LOXL2TAAR1L3MBTL1
SCHEMBL14536592 0.76 ESR1 (0.46) IDO1TAAR1L3MBTL1LMNACA1
SCHEMBL1149296 0.76 KMT2A (0.48) KMT2AIDO1TAAR1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 331 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110105255-B Mild synthesis method of diaryl thioether 江西理工大学 2020-11-03 CN claimed
CN-110452146-A Trifluoromethyl seleno-amino acids derivative and preparation method thereof UNIV WUHAN TECH 2019-11-15 CN claimed
EP-4741018-A2 SULPHONAMIDE COMPOUNDS Anaxis Pharma Pty Ltd (AU) 2026-05-13 EP disclosed
US-12583836-B2 Sulphonamide compounds Anaxis Pharma Pty Ltd (AU) 2026-03-24 US disclosed
US-12564583-B2 Small molecules against cereblon to enhance effector T cell function Lee Moffitt Cancer Center and Research Institute, Inc. (US) 2026-03-03 US disclosed
EP-4168401-B1 SULPHONAMIDE COMPOUNDS Anaxis Pharma Pty Ltd (AU) 2026-01-07 EP disclosed
US-20250388604-A1 Compounds and Their Use as PDE4 Activators MIRONID LIMITED (GB) 2025-12-25 US disclosed
EP-4572762-A1 COMPOUNDS AND THEIR USE AS PDE4 ACTIVATORS Mironid Limited (GB) 2025-06-25 EP disclosed
CN-119730854-A Compounds and their use as PDE4 activators 米罗尼德有限公司 2025-03-28 CN disclosed
US-20250074891-A1 BIFUNCTIONAL SULPHONAMIDE COMPOUNDS Anaxis Pharma Pty Ltd (AU) 2025-03-06 US disclosed
CN-119264303-A Pendant group functionalized fluorine-containing polymer, preparation method of fluorine-containing polymer, ion exchange membrane and application 佛山绿动氢能科技有限公司 2025-01-07 CN disclosed
WO-1995009158-A1 TRICYCLIC DERIVATIVES ZENECA LIMITED (GB) 1995-04-06 WO disclosed
EP-0627443-A1 3,4'-DIDEOXYMYCAMINOSYLTYLONOLIDE DERIVATIVE AND PRODUCTION THEREOF ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) 1994-12-07 EP disclosed
WO-1994007869-A1 QUINAZOLINE DERIVATIVES ZENECA LIMITED (GB) 1994-04-14 WO disclosed
EP-0169512-B1 NOVEL TYLOSIN DERIVATIVES Sanraku Incorporated (JP) 1988-09-28 EP disclosed
EP-0169512-A1 Novel tylosin derivatives Sanraku Incorporated (JP) 1986-01-29 EP disclosed
US-4257952-A PSYCHOTROPIC DRUGS, ANALGESICS, ANTIHISTAMINES STERLING DRUG INC. (US) 1981-03-24 US disclosed
US-4172834-A ANALGESICS, ANTIHISTAMINES AND PSYCHOTROPIC AGENTS STERLING DRUG INC. (US) 1979-10-30 US disclosed
US-4062864-A ANALGESIC, PSYCHOTROPIC, ANTIHISTAMINE STERLING DRUG INC. (US) 1977-12-13 US disclosed
US-3959309-A ANALGESICS, PSYCHOTROPIC, ANTIHISTAMINE STERLING DRUG INC. (US) 1976-05-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250074891-A1 BIFUNCTIONAL SULPHONAMIDE COMPOUNDS MLKL, RIPK3, CASP9 KMT2A 2755/4885IDO1 1078/4885LOXL2 801/4885
US-12583836-B2 Sulphonamide compounds MLKL, RIPK3, CASP1 KMT2A 3281/4885IDO1 687/4885LOXL2 739/4885
US-12564583-B2 Small molecules against cereblon to enhance effector T cell function CRBN, CD4, ICOS KMT2A 3331/4885IDO1 124/4885LOXL2 91/4885
US-20250388604-A1 Compounds and Their Use as PDE4 Activators PDE4A, PDE7A, PDE4B KMT2A 3462/4885IDO1 3249/4885LOXL2 2463/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.