Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.36 |
| ▸ | CA1 | P00915 | 4/20 | 0.36 |
| ▸ | CA9 | Q16790 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7507735 | 0.88 | LMNA (0.38) | — | |
| SCHEMBL7489122 | 0.84 | CA12 (0.36) | CA12CA1CA9 | |
| SCHEMBL7507165 | 0.81 | LMNA (0.34) | — | |
| SCHEMBL7505786 | 0.74 | GRM7 (0.35) | — | |
| SCHEMBL7916092 | 0.70 | P2RY2 (0.34) | — | |
| SCHEMBL7505700 | 0.67 | P2RY2 (0.46) | — | |
| SCHEMBL7488455 | 0.67 | ATAD2 (0.40) | — | |
| SCHEMBL7840803 | 0.65 | ATAD2 (0.38) | — | |
| SCHEMBL7500497 | 0.64 | P2RY2 (0.62) | — | |
| SCHEMBL7492166 | 0.63 | LMNA (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042320-B1 | NEW COMPOUNDS WHICH ARE P2-PURINOCEPTOR 7-TRANSMEMBRANE (TM) G-PROTEIN COUPLED RECEPTOR ANTAGONISTS | ASTRAZENECA UK LTD (GB) | 2002-02-13 | — | — | EP | disclosed |
| US-6218376-B1 | FOR TREATING INFLAMMATORY DISEASES | ASTRAZENECA UK LIMITED (GB) | 2001-04-17 | — | — | US | disclosed |