Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 11/20 | 0.53 |
| ▸ | MMP3 | P08254 | 9/20 | 0.53 |
| ▸ | MMP7 | P09237 | 6/20 | 0.53 |
| ▸ | MMP13 | P45452 | 4/20 | 0.53 |
| ▸ | MMP9 | P14780 | 6/20 | 0.51 |
| ▸ | MMP2 | P08253 | 4/20 | 0.51 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | MMP8 | P22894 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7503957 | 0.81 | MMP9 (0.53) | MMP1MMP3MMP7MMP13MMP9 | |
| SCHEMBL7569299 | 0.81 | MMP1 (0.52) | MMP1MMP3MMP7MMP13MMP9 | |
| SCHEMBL7505855 | 0.78 | MMP1 (0.48) | MMP1MMP3MMP7MMP13MMP9 | |
| SCHEMBL7512525 | 0.77 | MMP1 (0.53) | MMP1MMP3MMP7MMP13MMP9 | |
| SCHEMBL7511310 | 0.76 | MMP1 (0.50) | MMP1MMP3MMP7MMP13MMP9 | |
| SCHEMBL7508164 | 0.75 | ALDH1A1 (0.51) | MMP1MMP3MMP7MMP13MMP9 | |
| SCHEMBL7512979 | 0.74 | MMP1 (0.57) | MMP1MMP3MMP13MMP9ADAM17 | |
| SCHEMBL7513095 | 0.72 | KMT2A (0.47) | MMP1MMP3MMP7MMP13MMP9 | |
| SCHEMBL7550598 | 0.71 | ALDH1A1 (0.52) | MMP1MMP3MMP13MMP9MMP2 | |
| SCHEMBL7951436 | 0.71 | PKM (0.49) | MMP1MMP13MMP9MMP2ADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020006922-A1 | N-hydroxy-2-(alkyl, aryl, or heteroaryl sulfanyl, sulfinyl or sulfonyl)-3-substituted alkyl, aryl or heteroarylamides as matrix metalloproteinase inhibitors | AMERICAN CYANAMID COMPANY (US) | 2002-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020006922-A1 | N-hydroxy-2-(alkyl, aryl, or heteroaryl sulfanyl, sulfinyl or sulfonyl)-3-substituted alkyl, aryl or heteroarylamides as matrix metalloproteinase inhibitors | MMP12, ADAM33, MMP2 | MMP1 7/4885MMP3 8/4885MMP7 33/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.