Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | CSNK2A1 | P68400 | 5/20 | 0.47 |
| ▸ | CSNK2A2 | P19784 | 4/20 | 0.47 |
| ▸ | CSNK2B | P67870 | 4/20 | 0.47 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | DNA2 | P51530 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.39 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.37 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3613665 | 0.79 | BRPF1 (0.46) | CYP1A2HSD17B10CSNK2A1CSNK2A2CSNK2B | |
| SCHEMBL7512239 | 0.77 | DNA2 (0.56) | CYP1A2HSD17B10CSNK2A1CSNK2A2CSNK2B | |
| SCHEMBL7559605 | 0.75 | CSNK2A1 (0.43) | CYP1A2HSD17B10CSNK2A1CSNK2A2CSNK2B | |
| SCHEMBL1275907 | 0.73 | ADRA2A (0.50) | CYP1A2HSD17B10CSNK2A1CSNK2A2CSNK2B | |
| SCHEMBL2977498 | 0.72 | KDM4E (0.67) | CYP1A2HSD17B10CSNK2A1CSNK2A2CSNK2B | |
| Hydrochloric Acid SCHEMBL28606562 | 0.71 | KDM4E (0.65) | CYP1A2HSD17B10CSNK2A1CSNK2A2CSNK2B | |
| SCHEMBL2309708 | 0.69 | HSD17B10 (0.55) | CYP1A2HSD17B10CSNK2A1CSNK2A2CSNK2B | |
| SCHEMBL4339753 | 0.69 | CSNK2A2 (0.63) | CYP1A2HSD17B10CSNK2A1CSNK2A2CSNK2B | |
| SCHEMBL12708943 | 0.69 | CLEC4M (0.60) | CYP1A2HSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL10839866 | 0.68 | KDM4E (0.65) | CYP1A2HSD17B10CSNK2A1CSNK2A2CSNK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020193591-A1 | Process for producing 5-amino-8-alkylquinolonecarboxylic acid derivative and intermediates in the production thereof | DAIICHI PHARMACEUTICAL CO., LTD. | 2002-12-19 | — | — | US | disclosed |
| EP-1167344-A1 | PROCESS FOR PRODUCING 5-AMINO-8- ALKYLQUINOLO NECARBOXYLIC ACID DERIVATIVES AND INTERMEDIATES IN THE PRODUCTION THEREOF | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2002-01-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020193591-A1 | Process for producing 5-amino-8-alkylquinolonecarboxylic acid derivative and intermediates in the production thereof | SQOR, XDH, SPOUT1 | CYP1A2 255/4885HSD17B10 1257/4885CSNK2A1 1882/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.