Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | HPGD | P15428 | 2/20 | 0.67 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.64 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.63 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.63 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | DNA2 | P51530 | 1/20 | 0.61 |
| ▸ | CASP6 | P55212 | 1/20 | 0.61 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.61 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | CLEC4M | Q9H2X3 | 1/20 | 0.54 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28606562 | 0.98 | KDM4E (0.65) | KDM4EALDH1A1HPGDBRPF1CSNK2A2 | |
| SCHEMBL3978031 | 0.90 | BRPF1 (0.77) | KDM4EALDH1A1HPGDBRPF1CSNK2A2 | |
| SCHEMBL29950385 | 0.86 | BRPF1 (0.62) | KDM4EALDH1A1HPGDBRPF1CSNK2A2 | |
| SCHEMBL28287757 | 0.85 | RAB9A (0.60) | KDM4EALDH1A1HPGDBRPF1CSNK2A2 | |
| SCHEMBL18589537 | 0.85 | CSNK2A2 (0.69) | KDM4EALDH1A1HPGDCSNK2A2CSNK2B | |
| SCHEMBL28287764 | 0.83 | BRPF1 (0.59) | KDM4EALDH1A1HPGDBRPF1CSNK2A2 | |
| SCHEMBL1244916 | 0.82 | CSNK2A2 (0.65) | KDM4EALDH1A1HPGDCSNK2A2CSNK2B | |
| SCHEMBL9653780 | 0.82 | BRPF1 (0.57) | KDM4EALDH1A1HPGDBRPF1TSHR | |
| SCHEMBL2977296 | 0.81 | TSHR (0.64) | KDM4EALDH1A1HPGDCSNK2A2CSNK2B | |
| SCHEMBL28287748 | 0.81 | ALDH1A1 (0.60) | KDM4EALDH1A1HPGDBRPF1CSNK2A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7514451-B2 | 7-(4-Substituted-3-cyclopropylaminomethyl-1 pyrrolidinyl) quinolonecarboxylic acid derivative | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2009-04-07 | — | — | US | claimed |
| US-12377079-B2 | Antibacterial compounds and uses thereof | THE CHILDREN'S MEDICAL CENTER CORPORATION | 2025-08-05 | — | — | US | disclosed |
| CN-113185505-B | Quinolone oxazolidinone compound and preparation method and application thereof | 中国农业大学 | 2022-09-27 | — | — | CN | disclosed |
| US-20220023270-A1 | ANTIBACTERIAL COMPOUNDS AND USES THEREOF | THE CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2022-01-27 | — | — | US | disclosed |
| CN-113185505-A | Quinolone oxazolidinone compound and preparation method and application thereof | 中国农业大学 | 2021-07-30 | — | — | CN | disclosed |
| US-20170066722-A1 | AGENTS FOR USE IN THE TREATMENT OF CARDIOVASCULAR AND INFLAMMATORY DISEASES STRUCTURALLY BASED ON 4(1 H)-QUINOLONE | UCL BUSINESS PLC (GB) | 2017-03-09 | — | — | US | disclosed |
| US-20170066722-A1 | AGENTS FOR USE IN THE TREATMENT OF CARDIOVASCULAR AND INFLAMMATORY DISEASES STRUCTURALLY BASED ON 4(1 H)-QUINOLONE | UCL BUSINESS PLC (GB) | 2017-03-09 | — | — | US | disclosed |
| US-20140343098-A1 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2014-11-20 | — | — | US | disclosed |
| US-8802700-B2 | Modulators of ATP-Binding Cassette transporters | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2014-08-12 | — | — | US | disclosed |
| US-8614327-B2 | Modulators of ATP-binding cassette transporters | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2013-12-24 | — | — | US | disclosed |
| US-20130165442-A1 | Modulators of ATP-Binding Cassette Transporters | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2013-06-27 | — | — | US | disclosed |
| US-8354427-B2 | Modulators of ATP-binding cassette transporters | VERTEX PHARMACEUTICAL INCORPORATED (US) | 2013-01-15 | — | — | US | disclosed |
| US-20120309758-A1 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2012-12-06 | — | — | US | disclosed |
| EP-1857453-B1 | FLUOROALKYLPYRROLIDINE DERIVATIVES | DAIICHI SANKYO CO LTD (JP) | 2010-12-29 | — | — | EP | disclosed |
| US-20100184739-A1 | Modulators of ATP-Binding Cassette Transporters | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2010-07-22 | — | — | US | disclosed |
| US-20090012119-A1 | FLUOROALKYLPYRROLIDINE DERIVATIVE | DAIICHI SANKYO COMPANY LIMITED (JP) | 2009-01-08 | — | — | US | disclosed |
| EP-1857453-A1 | FLUOROALKYLPYRROLIDINE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2007-11-21 | — | — | EP | disclosed |
| US-20020193591-A1 | Process for producing 5-amino-8-alkylquinolonecarboxylic acid derivative and intermediates in the production thereof | DAIICHI PHARMACEUTICAL CO., LTD. | 2002-12-19 | — | — | US | disclosed |
| EP-1167344-A1 | PROCESS FOR PRODUCING 5-AMINO-8- ALKYLQUINOLO NECARBOXYLIC ACID DERIVATIVES AND INTERMEDIATES IN THE PRODUCTION THEREOF | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2002-01-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130165442-A1 | Modulators of ATP-Binding Cassette Transporters | CFTR, ABCB1, ABCC2 | KDM4E 4262/4885ALDH1A1 2165/4885HPGD 1121/4885 |
| US-20020193591-A1 | Process for producing 5-amino-8-alkylquinolonecarboxylic acid derivative and intermediates in the production thereof | SQOR, XDH, SPOUT1 | KDM4E 991/4885ALDH1A1 1145/4885HPGD 404/4885 |
| US-20100184739-A1 | Modulators of ATP-Binding Cassette Transporters | CFTR, ABCB1, ABCC2 | KDM4E 4262/4885ALDH1A1 2165/4885HPGD 1121/4885 |
| US-20140343098-A1 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | CFTR, ABCB1, ABCC2 | KDM4E 4262/4885ALDH1A1 2165/4885HPGD 1121/4885 |
| US-20170066722-A1 | AGENTS FOR USE IN THE TREATMENT OF CARDIOVASCULAR AND INFLAMMATORY DISEASES STRUCTURALLY BASED ON 4(1 H)-QUINOLONE | CBR3, AGTR1, CBR1 | KDM4E 4288/4885ALDH1A1 3209/4885HPGD 1392/4885 |
| US-12377079-B2 | Antibacterial compounds and uses thereof | CLPP, SPOUT1, MRPL21 | KDM4E 4451/4885ALDH1A1 2700/4885HPGD 1354/4885 |
| US-20220023270-A1 | ANTIBACTERIAL COMPOUNDS AND USES THEREOF | CLPP, SPOUT1, MRPL21 | KDM4E 4451/4885ALDH1A1 2700/4885HPGD 1354/4885 |
| US-20120309758-A1 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | CFTR, ABCB1, ABCC2 | KDM4E 4262/4885ALDH1A1 2165/4885HPGD 1121/4885 |
| US-20090012119-A1 | FLUOROALKYLPYRROLIDINE DERIVATIVE | FPR1, VIP, Q6ZSR9 | KDM4E 2389/4885ALDH1A1 2123/4885HPGD 2256/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.