Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MYB | P10242 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.36 |
| ▸ | RELA | Q04206 | 2/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 6/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1699832 | 0.84 | ALDH1A1 (0.34) | MAPTCYP2A6CYP1B1KMT2AMEN1 | |
| SCHEMBL26289822 | 0.83 | ALDH1A1 (0.32) | CYP2A6CYP1B1ALDH1A1TDP1HIF1A | |
| SCHEMBL8978539 | 0.83 | MYB (0.34) | RAB9AMYBMAPTNFKB1NFKB2 | |
| SCHEMBL30263642 | 0.81 | MAPT (0.38) | RAB9AMYBMAPTABCG2CYP1A2 | |
| SCHEMBL9035449 | 0.81 | NFKB1 (0.41) | RAB9AMYBMAPTNFKB1NFKB2 | |
| SCHEMBL29386725 | 0.80 | MEN1 (0.33) | RAB9AMAPTNFKB1NFKB2RELA | |
| SCHEMBL5615531 | 0.79 | ALDH1A1 (0.43) | RAB9AMAPTNFKB1NFKB2RELA | |
| SCHEMBL14291822 | 0.79 | NPC1 (0.32) | NPC1 | |
| SCHEMBL6995620 | 0.79 | GPR84 (0.38) | RAB9AMAPTNFKB1NFKB2RELA | |
| SCHEMBL8315808 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7332260-B2 | Naphthopyrans annelated in C5-C6, their preparation and compositions and (CO)polymer matrices containing them | CORNING INCORPORATED (US) | 2008-02-19 | — | — | US | disclosed |
| US-20020173667-A1 | NOVEL AROMATIC SUBSTITUTED NAPHTHOPYRANS | TRANSITIONS OPTICAL LIMITED (IE) | 2002-11-21 | — | — | US | disclosed |
| US-6478989-B1 | Aromatic substituted naphthopyrans | TRANSITIONS OPTICAL, INC. | 2002-11-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020173667-A1 | NOVEL AROMATIC SUBSTITUTED NAPHTHOPYRANS | TYR, B3GNT2, PAH | RAB9A 3013/4885MYB 348/4885MAPT 1590/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.