Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | PABPC1 | P11940 | 4/20 | 0.51 |
| ▸ | EIF4H | Q15056 | 4/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.51 |
| ▸ | CLK1 | P49759 | 2/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7531401 | 0.89 | KDM4E (0.52) | HTTLMNATP53ALOX15TSHR | |
| SCHEMBL7531707 | 0.85 | RECQL (0.60) | HTTLMNATSHRMCL1ALDH1A1 | |
| SCHEMBL7531709 | 0.84 | SLC40A1 (0.65) | HTTLMNAOPRK1NPSR1TDP1 | |
| SCHEMBL7530687 | 0.80 | HTT (0.48) | HTTTDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL6981434 | 0.80 | CLK1 (0.68) | HTTLMNATP53ALOX15TSHR | |
| SCHEMBL7569455 | 0.80 | KDM4E (0.67) | HTTTP53ALOX15TSHRNPSR1 | |
| SCHEMBL7533688 | 0.80 | PABPC1 (0.56) | HTTLMNATDP1PABPC1ALDH1A1 | |
| SCHEMBL7531142 | 0.79 | POLB (0.59) | LMNATSHRNPSR1TDP1ALDH1A1 | |
| SCHEMBL7533592 | 0.78 | METAP2 (0.46) | HTTLMNATSHRTDP1ALDH1A1 | |
| SCHEMBL7531823 | 0.77 | MAPT (0.55) | HTTLMNATSHRNPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | claimed |