Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 2/20 | 0.46 |
| ▸ | METAP1 | P53582 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.45 |
| ▸ | SLC40A1 | Q9NP59 | 6/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | ACLY | P53396 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | G6PD | P11413 | 1/20 | 0.41 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7537224 | 0.97 | ACLY (0.47) | METAP2METAP1RECQLSLC40A1HTR1A | |
| SCHEMBL7531707 | 0.83 | RECQL (0.60) | METAP2METAP1RECQLKMT2AMEN1 | |
| SCHEMBL7531142 | 0.80 | POLB (0.59) | METAP2METAP1KMT2AMEN1TDP1 | |
| SCHEMBL7531709 | 0.79 | SLC40A1 (0.65) | METAP2METAP1SLC40A1KMT2AMEN1 | |
| SCHEMBL3168431 | 0.78 | SCN3A (0.61) | RECQLKMT2AMEN1TDP1ALDH1A1 | |
| SCHEMBL7531380 | 0.78 | HTT (0.52) | KMT2AMEN1TDP1ALDH1A1MAPT | |
| SCHEMBL7531704 | 0.78 | ALDH1A1 (0.57) | RECQLGRM4KMT2AMEN1ACLY | |
| SCHEMBL7530687 | 0.77 | HTT (0.48) | METAP2METAP1RECQLSLC40A1KMT2A | |
| SCHEMBL7530791 | 0.77 | POLB (0.56) | METAP2METAP1KMT2AMEN1ACLY | |
| SCHEMBL7533688 | 0.76 | PABPC1 (0.56) | METAP2METAP1RECQLSLC40A1GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | claimed |