Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 11/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.65 |
| ▸ | GLO1 | Q04760 | 6/20 | 0.65 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.65 |
| ▸ | NFKBIA | P25963 | 2/20 | 0.65 |
| ▸ | G6PD | P11413 | 1/20 | 0.65 |
| ▸ | METAP2 | P50579 | 1/20 | 0.65 |
| ▸ | METAP1 | P53582 | 1/20 | 0.65 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.65 |
| ▸ | ATM | Q13315 | 1/20 | 0.65 |
| ▸ | KDR | P35968 | 1/20 | 0.55 |
| ▸ | MMP2 | P08253 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | MITF | O75030 | 1/20 | 0.52 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7531380 | 0.84 | HTT (0.52) | TDP1KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL7531707 | 0.83 | RECQL (0.60) | METAP2METAP1MMP2KMT2AMEN1 | |
| SCHEMBL7530687 | 0.81 | HTT (0.48) | SLC40A1TDP1GLO1AGTR1NFKBIA | |
| SCHEMBL7569455 | 0.81 | KDM4E (0.67) | TDP1ATMKMT2AMEN1ALDH1A1 | |
| SCHEMBL7533688 | 0.81 | PABPC1 (0.56) | SLC40A1TDP1GLO1AGTR1NFKBIA | |
| SCHEMBL442367 | 0.80 | SLC40A1 (1.00) | SLC40A1TDP1GLO1AGTR1NFKBIA | |
| SCHEMBL7531142 | 0.80 | POLB (0.59) | TDP1METAP2METAP1KMT2AMEN1 | |
| SCHEMBL7533592 | 0.79 | METAP2 (0.46) | SLC40A1TDP1GLO1AGTR1NFKBIA | |
| SCHEMBL7746129 | 0.79 | SLC40A1 (0.97) | SLC40A1TDP1GLO1AGTR1NFKBIA | |
| SCHEMBL7531823 | 0.78 | MAPT (0.55) | KMT2AMEN1ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | claimed |
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | disclosed |