Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | HTR2A | P28223 | 1/20 | 0.61 |
| ▸ | HTR2C | P28335 | 1/20 | 0.61 |
| ▸ | DRD2 | P14416 | 1/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.53 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.52 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10989753 | 0.77 | DRD2 (0.60) | KDM4EDRD2SIGMAR1CHRM2CHRM3 | |
| SCHEMBL9720716 | 0.77 | OPRD1 (0.70) | CYP1A2CYP3A4CYP2D6HTR2ADRD2 | |
| Glemanserin SCHEMBL120012 | 0.76 | HTR2A (1.00) | KDM4ECYP1A2CYP3A4CYP2D6TSHR | |
| SCHEMBL1505839 | 0.76 | SLC6A3 (0.67) | — | |
| SCHEMBL23198112 | 0.76 | DRD2 (0.58) | DRD2SIGMAR1CHRM2CHRM3 | |
| SCHEMBL10370183 | 0.76 | ACHE (0.65) | KDM4EDRD2SIGMAR1CHRM2CHRM3 | |
| SCHEMBL17967991 | 0.76 | DRD2 (0.58) | DRD2SIGMAR1PRMT6CHRM2CHRM3 | |
| SCHEMBL30516676 | 0.75 | SIGMAR1 (0.61) | KDM4ECYP1A2CYP3A4CYP2D6TSHR | |
| SCHEMBL25273950 | 0.75 | KDM4E (0.56) | KDM4ECYP1A2CYP3A4CYP2D6TSHR | |
| SCHEMBL31207846 | 0.75 | CARM1 (0.68) | KDM4ECYP1A2CYP3A4CYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1032569-A1 | IMIDAZOLE DERIVATIVES, PREPARATION AND THERAPEUTIC APPLICATION THEREOF | SANOFI-SYNTHELABO (FR) | 2000-09-06 | — | — | EP | claimed |
| WO-1999025710-A1 | IMIDAZOLE DERIVATIVES, PREPARATION AND THERAPEUTIC APPLICATION THEREOF | SANOFI-SYNTHELABO (FR) | 1999-05-27 | — | — | WO | claimed |