SCHEMBL7537241

SCHEMBL7537241

CC(C)c1ccc(C(C)C)c(N(C)C)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.39
TRPA1 O75762 2/20 0.38
PTGS1 P23219 1/20 0.38
CACNA1C Q13936 1/20 0.38
ALDH1A1 P00352 2/20 0.36
GAA P10253 1/20 0.36
ALOX12 P18054 1/20 0.36
HTT P42858 1/20 0.36
HIF1A Q16665 1/20 0.36
RNASEH1 O60930 1/20 0.34
TYR P14679 2/20 0.33
GABRA1 P14867 1/20 0.33
GABRB2 P47870 1/20 0.33
CHRM1 P11229 1/20 0.33
SLC6A2 P23975 1/20 0.33
ADRA1A P35348 1/20 0.33
HTR2B P41595 1/20 0.33
HTR1D P28221 1/20 0.33
HTR1B P28222 1/20 0.33
FABP3 P05413 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20368242 0.86 TRPA1 (0.31) LMNATRPA1CHRM1SLC6A2ADRA1A
SCHEMBL12248233 0.83 LMNA (0.39) LMNATRPA1PTGS1CACNA1CALDH1A1
SCHEMBL14200344 0.82 LMNA (0.41) LMNATRPA1PTGS1CACNA1CALDH1A1
SCHEMBL20368249 0.80 ALDH1A1 (0.38) ALDH1A1GAAALOX12HTTHIF1A
SCHEMBL20285948 0.78 TRPA1 (0.52) LMNATRPA1ALDH1A1CHRM1SLC6A2
SCHEMBL14228579 0.78 LMNA (0.54) LMNATRPA1PTGS1CACNA1CALDH1A1
SCHEMBL24497708 0.77 CYP19A1 (0.38) LMNATRPA1PTGS1CACNA1CALDH1A1
SCHEMBL18999634 0.77 HTR1D (0.40) LMNATRPA1PTGS1CACNA1CALDH1A1
SCHEMBL21725473 0.77 KMT2A (0.47) LMNATRPA1ALDH1A1GAAHTT
SCHEMBL21756916 0.77 GABRA1 (0.39) LMNATRPA1ALDH1A1GABRA1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250271753-A1 MICROCAPSULE IMAGING SYSTEM INCLUDING NON-PHOTOPOLYMERIZABLE REACTIVE DILUENT POLAROID IP B.V. (NL) 2025-08-28 US disclosed
US-12321095-B2 Microcapsule imaging system including non-photopolymerizable reactive diluent POLAROID IP B.V. (NL) 2025-06-03 US disclosed
EP-4537160-A1 MICROCAPSULE IMAGING SYSTEM INCLUDING NON-PHOTOPOLYMERIZABLE REACTIVE DILUENT Polaroid IP B.V. (NL) 2025-04-16 EP disclosed
WO-2023237992-A1 MICROCAPSULE IMAGING SYSTEM INCLUDING NON-PHOTOPOLYMERIZABLE REACTIVE DILUENT POLAROID IP B.V. (NL) 2023-12-14 WO disclosed
US-20230393459-A1 MICROCAPSULE IMAGING SYSTEM INCLUDING NON-PHOTOPOLYMERIZABLE REACTIVE DILUENT POLAROID IP B.V. (NL) 2023-12-07 US disclosed
US-20230141913-A2 PHENOXY(HETERO)ARYL ETHERS OF ANTIPROLIFERACTIVE ACTIVITY Xeniopro GmbH (DE) 2023-05-11 US disclosed
US-20230141913-A2 PHENOXY(HETERO)ARYL ETHERS OF ANTIPROLIFERACTIVE ACTIVITY Xeniopro GmbH (DE) 2023-05-11 US disclosed
US-20220411426-A1 SUBSTRATE SELECTIVE INHIBITORS OF INSULIN-DEGRADING ENZYME (IDE) AND USES THEREOF PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2022-12-29 US disclosed
US-11040976-B2 Substrate selective inhibitors of insulin-degrading enzyme (IDE) and uses thereof PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2021-06-22 US disclosed
US-20190016723-A9 SUBSTRATE SELECTIVE INHIBITORS OF INSULIN-DEGRADING ENZYME (IDE) AND USES THEREOF PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2019-01-17 US disclosed
US-20180194768-A1 SUBSTRATE SELECTIVE INHIBITORS OF INSULIN DEGRADING ENZYME (IDE) AND USES THEREOF PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2018-07-12 US disclosed
US-8778874-B2 Glycopeptide antibiotic monomer derivatives NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) 2014-07-15 US disclosed
US-20080097078-A1 Antibacterial activity against vancomycin-resistant bacteria SHIONOGI & CO., LTD. (JP) 2008-04-24 US disclosed
CN-1097057-C Borate photoinitiators from polyboranes CIBA SC HOLDING AG (CH) 2002-12-25 CN disclosed
EP-1203999-A2 Photoinitiator comprising a borane and an electron donating compound Ciba SC Holding AG (CH) 2002-05-08 EP disclosed
EP-0775706-A2 Borates photoinitiators from polyboranes Ciba SC Holding AG (CH) 1997-05-28 EP disclosed
US-5411995-A Free radically curable formulations employing dithiolate catalysts LOCTITE CORPORATION (US) 1995-05-02 US disclosed
US-5230982-A Heterocyclic disulfides for crosslinking THE MEAD CORPORATION (US) 1993-07-27 US disclosed
US-5217760-A Of a dithiolate and an organic halogen compound and/or tertiary amine coinitiator LOCTITE CORPORATION (US) 1993-06-08 US disclosed
EP-0467649-A2 Free radically curable formulations employing dithiolate catalysts LOCTITE CORPORATION (US) 1992-01-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180194768-A1 SUBSTRATE SELECTIVE INHIBITORS OF INSULIN DEGRADING ENZYME (IDE) AND USES THEREOF IDE, SI, GPR119 LMNA 1974/4885TRPA1 4568/4885PTGS1 3824/4885
US-20220411426-A1 SUBSTRATE SELECTIVE INHIBITORS OF INSULIN-DEGRADING ENZYME (IDE) AND USES THEREOF IDE, SI, GPR119 LMNA 2054/4885TRPA1 4491/4885PTGS1 3340/4885
US-20190016723-A9 SUBSTRATE SELECTIVE INHIBITORS OF INSULIN-DEGRADING ENZYME (IDE) AND USES THEREOF IDE, SI, GPR119 LMNA 2131/4885TRPA1 4453/4885PTGS1 3755/4885
US-20230141913-A2 PHENOXY(HETERO)ARYL ETHERS OF ANTIPROLIFERACTIVE ACTIVITY AHR, MUSK, TYR LMNA 2488/4885TRPA1 2803/4885PTGS1 1708/4885
US-11040976-B2 Substrate selective inhibitors of insulin-degrading enzyme (IDE) and uses thereof IDE, SI, GPR119 LMNA 2131/4885TRPA1 4453/4885PTGS1 3755/4885
US-20080097078-A1 Antibacterial activity against vancomycin-resistant bacteria CSGALNACT1, MON2, NR2C2 LMNA 4466/4885TRPA1 4040/4885PTGS1 4716/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.