SCHEMBL8466889

SCHEMBL8466889

C=CCC1=CC([Si](C)(C)C2c3ccccc3-c3ccccc32)c2ccccc21

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TOP2A P11388 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8680298 0.97 TOP2A (0.30) TOP2A
SCHEMBL822007 0.84 TOP2A (0.34) TOP2A
SCHEMBL7544944 0.83 ACHE (0.33)
SCHEMBL8468840 0.79 HTR6 (0.39)
SCHEMBL7944622 0.74 GPR3 (0.34)
SCHEMBL5175634 0.71 GPR3 (0.46)
SCHEMBL30143298 0.70 HTR6 (0.37)
Hydrochloric Acid SCHEMBL8998656 0.70
Hydrochloric Acid SCHEMBL7559465 0.70
SCHEMBL7546253 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5886202-A HAVING UNUSUAL EFFECTIVENESS AS CATALYSTS FOR THE POLYMERIZATION OF OLEFINS WHEN CERTAIN SUBSTITUENTS ARE AT THE 3 POSITION OF THE INDENE; HIGHER-MOLECULAR-WEIGHT POLYOLEFINS CHEVRON PHILLIPS CHEMICAL COMPANY LP 1999-03-23 US disclosed
EP-0729978-A1 Polyethylene and method for production thereof PHILLIPS PETROLEUM COMPANY (US) 1996-09-04 EP disclosed