Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8466889 | 0.97 | TOP2A (0.32) | TOP2A | |
| SCHEMBL822007 | 0.82 | TOP2A (0.34) | TOP2A | |
| SCHEMBL7544944 | 0.81 | ACHE (0.33) | — | |
| SCHEMBL8468840 | 0.77 | HTR6 (0.39) | — | |
| Hydrochloric Acid SCHEMBL8998656 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL7559465 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL6559595 | 0.73 | GPR3 (0.43) | — | |
| SCHEMBL7944622 | 0.72 | GPR3 (0.34) | — | |
| Hydrochloric Acid SCHEMBL6295601 | 0.71 | HTR2A (0.37) | — | |
| Hydrochloric Acid SCHEMBL7766701 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998052686-A1 | METHOD FOR MAKING AND USING A PREPOLYMERIZED OLEFIN POLYMERIZATION CATALYST | PHILLIPS PETROLEUM COMPANY (US) | 1998-11-26 | — | — | WO | disclosed |