Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 4/20 | 0.31 |
| ▸ | NOS3 | P29474 | 3/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7546681 | 0.89 | TDP1 (0.37) | TDP1L3MBTL1NOS2NOS3TP53 | |
| SCHEMBL7548395 | 0.82 | ALOX5 (0.38) | L3MBTL1 | |
| SCHEMBL8815017 | 0.79 | — | — | |
| SCHEMBL7546276 | 0.79 | MEN1 (0.45) | NOS2NOS3 | |
| SCHEMBL7551330 | 0.78 | NAMPT (0.36) | TDP1L3MBTL1NOS2NOS3 | |
| SCHEMBL7546196 | 0.77 | KDM4E (0.38) | NOS2NOS3TP53PPARG | |
| SCHEMBL9059987 | 0.75 | SGMS2 (0.35) | TDP1L3MBTL1TP53 | |
| SCHEMBL7600813 | 0.74 | — | — | |
| SCHEMBL7553256 | 0.74 | RAB9A (0.40) | L3MBTL1 | |
| SCHEMBL8799386 | 0.72 | SHBG (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997049708-A9 | TRICYCLIC BENZAZEPINE VASOPRESSIN ANTAGONISTS | — | 1998-05-22 | — | — | WO | disclosed |