Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.35 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.35 |
| ▸ | SHBG | P04278 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | ANO1 | Q5XXA6 | 3/20 | 0.32 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | EIF2AK3 | Q9NZJ5 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7551790 | 0.89 | SGMS2 (0.36) | SGMS2NR3C2SHBGPDPK1LMNA | |
| SCHEMBL7546276 | 0.83 | MEN1 (0.45) | NR3C2SHBGANO1KDM4EMAPT | |
| SCHEMBL7550244 | 0.81 | MAPK14 (0.35) | NR3C2CHRNA7LMNATP53KMT2A | |
| SCHEMBL7548395 | 0.77 | ALOX5 (0.38) | L3MBTL1 | |
| SCHEMBL7600813 | 0.76 | — | — | |
| SCHEMBL7546252 | 0.75 | TDP1 (0.32) | TP53TDP1L3MBTL1 | |
| SCHEMBL8799386 | 0.74 | SHBG (0.44) | SHBGANO1KDM4EMAPK1MEN1 | |
| SCHEMBL7546196 | 0.74 | KDM4E (0.38) | KDM4ETP53KDM4C | |
| SCHEMBL7544426 | 0.73 | HPGD (0.42) | LMNAKDM4ETP53MAPTKDM4C | |
| SCHEMBL7547894 | 0.72 | MAPT (0.46) | NR3C2SHBGANO1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996022295-A9 | TRICYCLIC BENZAZEPINE VASOPRESSIN ANTAGONISTS | — | 1996-11-14 | — | — | WO | disclosed |