Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.47 |
| ▸ | PTGES2 | Q9H7Z7 | 3/20 | 0.45 |
| ▸ | ACLY | P53396 | 14/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.40 |
| ▸ | ACACA | Q13085 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7545504 | 0.83 | ACLY (0.48) | KIF11ACLY | |
| SCHEMBL7357115 | 0.77 | UQCRB (0.46) | KIF11 | |
| SCHEMBL7506954 | 0.76 | KIF11 (0.40) | KIF11PTGES2ACLYDHODH | |
| SCHEMBL24489581 | 0.71 | ESR2 (0.52) | PTGES2ACLYDHODHHTR6 | |
| SCHEMBL3375889 | 0.70 | PGR (0.55) | KIF11PTGES2ACLY | |
| SCHEMBL4491328 | 0.69 | KEAP1 (0.54) | — | |
| SCHEMBL27802067 | 0.66 | ALDH1A1 (0.56) | — | |
| SCHEMBL16389422 | 0.66 | ALDH1A1 (0.59) | DHODH | |
| SCHEMBL24359760 | 0.66 | ALDH1A1 (0.65) | DHODH | |
| SCHEMBL28783847 | 0.66 | MAPT (0.67) | PTGES2HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1216231-A2 | INHIBITORS OF FACTOR Xa | Millennium Pharmaceuticals, Inc. (US) | 2002-06-26 | — | — | EP | disclosed |
| WO-2001019798-A2 | INHIBITORS OF FACTOR Xa | COR THERAPEUTICS INC. (US) | 2001-03-22 | — | — | WO | disclosed |