Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 16/20 | 0.48 |
| ▸ | KIF11 | P52732 | 2/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7547560 | 0.83 | KIF11 (0.47) | ACLYKIF11 | |
| SCHEMBL7357115 | 0.77 | UQCRB (0.46) | KIF11 | |
| SCHEMBL7506708 | 0.76 | ACLY (0.44) | ACLYKIF11 | |
| SCHEMBL23702902 | 0.75 | ACLY (0.51) | ACLY | |
| SCHEMBL21931131 | 0.71 | ACLY (0.82) | ACLY | |
| SCHEMBL4491328 | 0.69 | KEAP1 (0.54) | — | |
| SCHEMBL17849564 | 0.69 | ACLY (0.59) | ACLY | |
| SCHEMBL4659840 | 0.68 | KIF11 (0.74) | KIF11 | |
| SCHEMBL5782639 | 0.68 | ABCB1 (0.43) | ACLYKIF11ABCB1 | |
| SCHEMBL4127360 | 0.68 | HTR6 (0.47) | ACLY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1216231-A2 | INHIBITORS OF FACTOR Xa | Millennium Pharmaceuticals, Inc. (US) | 2002-06-26 | — | — | EP | disclosed |
| WO-2001019798-A2 | INHIBITORS OF FACTOR Xa | COR THERAPEUTICS INC. (US) | 2001-03-22 | — | — | WO | disclosed |