Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13656499 | 0.86 | TSHR (0.40) | ALDH1A1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL26115241 | 0.79 | ALDH1A1 (0.47) | ALDH1A1RAB9ASMN1; SMN2MAPTGAA | |
| SCHEMBL10236415 | 0.78 | ALDH1A1 (0.43) | ALDH1A1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL6922760 | 0.76 | TSHR (0.40) | TSHRCASP1ESR2CHRNA7 | |
| SCHEMBL29177268 | 0.75 | TSHR (0.32) | ALDH1A1RAB9ATSHRCASP1 | |
| SCHEMBL14572069 | 0.73 | MEN1 (0.46) | ALDH1A1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL16095310 | 0.72 | ALDH1A1 (0.38) | ALDH1A1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL2041552 | 0.72 | — | — | |
| SCHEMBL13656503 | 0.71 | TSHR (0.50) | GAATSHRCASP1ESR2CHRNA7 | |
| SCHEMBL5670762 | 0.69 | LMNA (0.37) | ALDH1A1RAB9ASMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112574079-A | 2, 2-difluoro-N- (2-thioether cyclohexyl-1-alkene-1-base) acetamide and derivative and synthesis method thereof | 湖南工程学院 | 2021-03-30 | — | — | CN | claimed |
| WO-2003099757-A1 | STABILISATION OF ETHYLENICALLY UNSATURATED COMPOUNDS COMPRISING HYDROXYLAMINE DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 2003-12-04 | — | — | WO | claimed |
| CN-112574079-A | 2, 2-difluoro-N- (2-thioether cyclohexyl-1-alkene-1-base) acetamide and derivative and synthesis method thereof | 湖南工程学院 | 2021-03-30 | — | — | CN | disclosed |
| EP-2669342-B1 | ACTIVE-ENERGY-RAY-CURABLE INKJET INK COMPOSITION, ACTIVE-ENERGY-RAY-CURABLE INKJET INK, AND INKJET RECORDING METHOD | KONICA MINOLTA INC (JP) | 2020-03-18 | — | — | EP | disclosed |
| US-10011559-B2 | Preparation of chiral amides and amines | SUNOVION PHARMACEUTICALS INC. (US) | 2018-07-03 | — | — | US | disclosed |
| US-10011559-B2 | Preparation of chiral amides and amines | SUNOVION PHARMACEUTICALS INC. (US) | 2018-07-03 | — | — | US | disclosed |
| US-20180016224-A1 | PREPARATION OF CHIRAL AMIDES AND AMINES | SUNOVION PHARMACEUTICALS INC. | 2018-01-18 | — | — | US | disclosed |
| US-20180016224-A1 | PREPARATION OF CHIRAL AMIDES AND AMINES | SUNOVION PHARMACEUTICALS INC. | 2018-01-18 | — | — | US | disclosed |
| EP-2816024-B1 | Chiral amines | SUNOVION PHARMACEUTICALS INC (US) | 2017-08-02 | — | — | EP | disclosed |
| US-9416289-B2 | Active-energy-ray-curable inkjet ink composition, active-energy-ray-curable inkjet ink, and inkjet recording method | Konica Minolta, Inc. (JP) | 2016-08-16 | — | — | US | disclosed |
| US-9411226-B2 | Chemically amplified resist composition and patterning process | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2016-08-09 | — | — | US | disclosed |
| WO-2007115185-A2 | PREPARATION OF CHIRAL AMIDES AND AMINES | SEPRACOR INC. (US) | 2007-10-11 | — | — | WO | disclosed |
| WO-2007063031-A2 | STABILIZED POLYMERIZABLE MIXTURES | BASF AKTIENGESELLSCHAFT (DE) | 2007-06-07 | — | — | WO | disclosed |
| US-20060287548-A1 | Radical interceptors as stabilizers of polymerizable compounds | BASF AKTIENGESELLSCHAFT (DE) | 2006-12-21 | — | — | US | disclosed |
| EP-1670877-A1 | RADICAL INTERCEPTORS AS STABILIZERS OF POLYMERIZABLE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2006-06-21 | — | — | EP | disclosed |
| US-20050256185-A1 | Spiro and dispiro 1,2,4-trioxolane antimalarials | MEDICINES FOR MALARIA VENTURE MMV (CH) | 2005-11-17 | — | — | US | disclosed |
| WO-2005030907-A1 | RADICAL INTERCEPTORS AS STABILIZERS OF POLYMERIZABLE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2005-04-07 | — | — | WO | disclosed |
| EP-1518916-A1 | Scavenger of free radicals as stabilizers of polymerisable compounds | BASF AKTIENGESELLSCHAFT (DE) | 2005-03-30 | — | — | EP | disclosed |
| WO-2003099757-A1 | STABILISATION OF ETHYLENICALLY UNSATURATED COMPOUNDS COMPRISING HYDROXYLAMINE DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 2003-12-04 | — | — | WO | disclosed |
| WO-2003035596-A2 | INHIBITOR MIXTURE FOR (METH)ACRYLIC ACID AND (METH)ACRYLIC ACID ESTER | BASF AKTIENGESELLSCHAFT (DE) | 2003-05-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10011559-B2 | Preparation of chiral amides and amines | PNMT, ALKBH5, ALKBH2 | ALDH1A1 501/4885RAB9A 4638/4885SMN1; SMN2 1039/4885 |
| US-20180016224-A1 | PREPARATION OF CHIRAL AMIDES AND AMINES | PNMT, ALKBH2, ALKBH5 | ALDH1A1 523/4885RAB9A 4717/4885SMN1; SMN2 1006/4885 |
| US-20060287548-A1 | Radical interceptors as stabilizers of polymerizable compounds | TTPA, AADAT, TSPO | ALDH1A1 1648/4885RAB9A 3837/4885SMN1; SMN2 3250/4885 |
| US-20050256185-A1 | Spiro and dispiro 1,2,4-trioxolane antimalarials | DHODH, THPO, SQLE | ALDH1A1 212/4885RAB9A 573/4885SMN1; SMN2 2959/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.