Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR5 | Q9H228 | 12/20 | 0.53 |
| ▸ | MMP1 | P03956 | 3/20 | 0.49 |
| ▸ | MMP9 | P14780 | 2/20 | 0.49 |
| ▸ | MMP13 | P45452 | 2/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.48 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27555705 | 0.92 | S1PR5 (0.54) | S1PR5MMP1MMP9MMP13S1PR1 | |
| SCHEMBL7619211 | 0.92 | S1PR5 (0.53) | S1PR5MMP1MMP9MMP13S1PR1 | |
| Hydroxyamine SCHEMBL7463488 | 0.90 | S1PR5 (0.52) | S1PR5MMP1MMP9MMP13S1PR1 | |
| SCHEMBL7512543 | 0.89 | TAS2R14 (0.50) | MMP1MMP9MMP13ADAM17KMT2A | |
| Hydroxyamine SCHEMBL7463594 | 0.86 | HRH3 (0.55) | S1PR5MMP1MMP9MMP13S1PR1 | |
| SCHEMBL7509653 | 0.83 | CCR8 (0.49) | S1PR5MMP1MMP9MMP13S1PR1 | |
| SCHEMBL7952260 | 0.83 | LTA4H (0.52) | S1PR5MMP1MMP9MMP13HRH3 | |
| Hydroxyamine SCHEMBL7462750 | 0.81 | KCNH2 (0.46) | S1PR5MMP1MMP9MMP13S1PR1 | |
| SCHEMBL6863576 | 0.81 | ADAM17 (0.56) | S1PR5MMP1MMP9MMP13S1PR1 | |
| SCHEMBL7506020 | 0.81 | S1PR5 (0.53) | S1PR5MMP1MMP9MMP13S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020006922-A1 | N-hydroxy-2-(alkyl, aryl, or heteroaryl sulfanyl, sulfinyl or sulfonyl)-3-substituted alkyl, aryl or heteroarylamides as matrix metalloproteinase inhibitors | AMERICAN CYANAMID COMPANY (US) | 2002-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020006922-A1 | N-hydroxy-2-(alkyl, aryl, or heteroaryl sulfanyl, sulfinyl or sulfonyl)-3-substituted alkyl, aryl or heteroarylamides as matrix metalloproteinase inhibitors | MMP12, ADAM33, MMP2 | S1PR5 991/4885MMP1 7/4885MMP9 16/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.