SCHEMBL755601

SCHEMBL755601

c1ccc(Cc2cnc(-c3cc(-c4ncc(Cc5ccccc5)n4-c4ccccc4)cc(-c4ncc(Cc5ccccc5)n4-c4ccccc4)c3)n2-c2ccccc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.39
ALDH1A1 P00352 2/20 0.39
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
IDH1 O75874 3/20 0.36
POLB P06746 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
CALM1 P0DP23 1/20 0.34
TAAR1 Q96RJ0 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
HPGDS O60760 1/20 0.34
TBXAS1 P24557 1/20 0.34
CTSS P25774 1/20 0.33
CTSK P43235 1/20 0.33
CYP11B1 P15538 1/20 0.33
CYP11B2 P19099 1/20 0.33
BRD4 O60885 1/20 0.33
MLYCD O95822 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL346644 0.74 ALDH1A1 (0.45) HPGDALDH1A1NPC1RAB9APOLB
SCHEMBL28107653 0.69 HSD11B1 (0.50) HPGDALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL7912421 0.67 AVPR1A (0.44) HPGDALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL16382564 0.66 ALDH1A1 (0.46) ALDH1A1RAB9AIDH1MEN1KMT2A
SCHEMBL18492713 0.66 ALDH1A1 (0.46) HPGDALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL7062228 0.65 AVPR1A (0.50) HPGDALDH1A1NPC1RAB9AMEN1
SCHEMBL11978680 0.65 MEN1 (0.50) HPGDALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL4402513 0.64 AVPR1A (0.63) HPGDALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL5378064 0.63 PI4KA (0.51) HPGDALDH1A1NPC1RAB9AMEN1
SCHEMBL15989423 0.63 ALDH1A1 (0.46) HPGDALDH1A1MEN1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11692131-B2 Heteroleptic transition metal-carbene complexes and their use in organic light-emitting diodes UDC IRELAND LIMITED (IE) 2023-07-04 US disclosed
US-20190322929-A1 HETEROLEPTIC TRANSITION METAL-CARBENE COMPLEXES AND THEIR USE IN ORGANIC LIGHT-EMITTING DIODES UDC IRELAND LTD (IE) 2019-10-24 US disclosed
US-10385263-B2 Heteroleptic transition metal-carbene complexes and their use in organic light-emitting diodes (OLEDS) UDC IRELAND LIMITED (IE) 2019-08-20 US disclosed
US-8373159-B2 Organic light-emitting diodes comprising carbene-transition metal complex emitter, and at least one compound selected from disilylcarbazoles, disilyldibenzofurans, disilyldibenzothiophenes, disilyldibenzophospholes, disilyldibenzothiophene s-oxides and disilyldibe BASF SE (DE) 2013-02-12 US disclosed
EP-2007779-B1 HETEROLEPTIC TRANSITION METAL-CARBENE COMPLEXES AND THEIR USE IN ORGANIC LIGHT-EMITTING DIODES (OLEDS) BASF SE (DE) 2012-03-21 EP disclosed
US-7989091-B2 Silanes containing phenothiazine-S-oxide or phenothiazine-S,S-dioxide groups and the use thereof in OLEDs BASF SE (DE) 2011-08-02 US disclosed
EP-2150556-B1 SILANES CONTAINING PHENOTHIAZINE-S-OXIDE OR PHENOTHIAZINE-S,S-DIOXIDE GROUPS AND THE USE THEREOF IN OLEDS BASF SE (DE) 2011-01-12 EP disclosed
US-20100219403-A1 ORGANIC LIGHT-EMITTING DIODES COMPRISING CARBENE-TRANSITION METAL COMPLEX EMITTERS, AND AT LEAST ONE COMPOUND SELECTED FROM DISILYLCARBAZOLES, DISILYLDIBENZOFURANS, DISILYLDIBENZOTHIOPHENES, DISILYLDIBENZOPHOSPHOLES, DISILYLDIBENZOTHIOPHENE S-OXIDES AND DISILYLDIBENZOTHIOPHENE S,S-DIOXIDES BASF SE (DE) 2010-09-02 US disclosed
US-20100187980-A1 SILANES CONTAINING PHENOTHIAZINE-S-OXIDE OR PHENOTHIAZINE-S,S-DIOXIDE GROUPS AND THE USE THEREOF IN OLEDS BASF SE (DE) 2010-07-29 US disclosed
US-20090096367-A1 HETEROLEPTIC TRANSITION METAL-CARBENE COMPLEXES AND THEIR USE IN ORGANIC LIGHT-EMITTING DIODES (OLEDS) BASF SE (DE) 2009-04-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090096367-A1 HETEROLEPTIC TRANSITION METAL-CARBENE COMPLEXES AND THEIR USE IN ORGANIC LIGHT-EMITTING DIODES (OLEDS) OCIAD2, OCIAD1, ICOSLG HPGD 2336/4885ALDH1A1 1119/4885NPC1 1462/4885
US-20100187980-A1 SILANES CONTAINING PHENOTHIAZINE-S-OXIDE OR PHENOTHIAZINE-S,S-DIOXIDE GROUPS AND THE USE THEREOF IN OLEDS OPRD1, PPID, PLOD2 HPGD 920/4885ALDH1A1 980/4885NPC1 3244/4885
US-20100219403-A1 ORGANIC LIGHT-EMITTING DIODES COMPRISING CARBENE-TRANSITION METAL COMPLEX EMITTERS, AND AT LEAST ONE COMPOUND SELECTED FROM DISILYLCARBAZOLES, DISILYLDIBENZOFURANS, DISILYLDIBENZOTHIOPHENES, DISILYLDIBENZOPHOSPHOLES, DISILYLDIBENZOTHIOPHENE S-OXIDES AND DISILYLDIBENZOTHIOPHENE S,S-DIOXIDES DDT, GRIN2B, DRD1 HPGD 2360/4885ALDH1A1 1149/4885NPC1 4251/4885
US-20190322929-A1 HETEROLEPTIC TRANSITION METAL-CARBENE COMPLEXES AND THEIR USE IN ORGANIC LIGHT-EMITTING DIODES CLTB, CLTC, CYBA HPGD 3859/4885ALDH1A1 1498/4885NPC1 3001/4885
US-11692131-B2 Heteroleptic transition metal-carbene complexes and their use in organic light-emitting diodes CLTB, CLTC, CYBA HPGD 3859/4885ALDH1A1 1498/4885NPC1 3001/4885
US-10385263-B2 Heteroleptic transition metal-carbene complexes and their use in organic light-emitting diodes (OLEDS) OCIAD2, OCIAD1, ICOSLG HPGD 2336/4885ALDH1A1 1119/4885NPC1 1462/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.