SCHEMBL346644

SCHEMBL346644

c1ccc(Cc2ncc(-c3cc(-c4cnc(Cc5ccccc5)n4-c4ccccc4)cc(-c4cnc(Cc5ccccc5)n4-c4ccccc4)c3)n2-c2ccccc2)cc1

nearest known ligand 0.45

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.45
HPGD P15428 3/20 0.45
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
FYN P06241 5/20 0.38
POLB P06746 2/20 0.38
GAA P10253 1/20 0.38
KDM4E B2RXH2 1/20 0.36
PPARG P37231 1/20 0.36
NCOA2 Q15596 1/20 0.36
NCOA1 Q15788 1/20 0.36
TDP1 Q9NUW8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18492713 0.92 ALDH1A1 (0.46) ALDH1A1HPGDNPC1RAB9AFYN
SCHEMBL755601 0.74 HPGD (0.39) ALDH1A1HPGDNPC1RAB9APOLB
SCHEMBL15983599 0.69 HSD11B1 (0.53) ALDH1A1FYNKDM4ETDP1
SCHEMBL7062228 0.65 AVPR1A (0.50) ALDH1A1HPGDNPC1RAB9AGAA
SCHEMBL346645 0.65 NPC1 (0.40) ALDH1A1HPGDNPC1RAB9APOLB
SCHEMBL3814453 0.65 ALDH1A1 (0.52) ALDH1A1HPGDNPC1RAB9APOLB
SCHEMBL4402513 0.64 AVPR1A (0.63) ALDH1A1HPGDKDM4E
SCHEMBL24890358 0.63 AVPR1A (0.58) ALDH1A1HPGDNPC1RAB9AGAA
SCHEMBL8656696 0.63 CYP1A2 (0.42) ALDH1A1HPGDNPC1RAB9AFYN
SCHEMBL8022032 0.63 NPC1 (0.65) ALDH1A1NPC1RAB9AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 125 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12622170-B2 Fluorescent organic light emitting elements having high efficiency UDC Ireland (IE) 2026-05-05 US disclosed
US-12538704-B2 4H-imidazo[1,2-a]imidazoles for electronic applications UDC IRELAND LIMITED (IE) 2026-01-27 US disclosed
US-20230380277-A1 Fluorescent Organic Light Emitting Elements Having High Efficiency UDC IRELAND LTD (IE) 2023-11-23 US disclosed
US-11744152-B2 Benzimidazo[1,2-a]benzimidazole derivatives for electronic applications UDC IRELAND LIMITED (IE) 2023-08-29 US disclosed
US-11706978-B2 Fluorescent organic light emitting elements having high efficiency UDC IRELAND LIMITED (IE) 2023-07-18 US disclosed
US-20230090208-A1 4H-Imidazo[1,2-a]imidazoles for Electronic Applications UDC IRELAND LTD (IE) 2023-03-23 US disclosed
US-11450812-B2 4H-imidazo[1,2-a]imidazoles for electronic applications UDC IRELAND LIMITED (IE) 2022-09-20 US disclosed
EP-3356369-B1 BENZIMIDAZOLO[1,2-A]BENZIMIDAZOLE CARRYING TRIAZINE GROUPS FOR ORGANIC LIGHT EMITTING DIODES IDEMITSU KOSAN CO (JP) 2022-05-04 EP disclosed
EP-3640252-B1 4H-IMIDAZO[1,2-A]IMIDAZOLES FOR ELECTRONIC APPLICATIONS UDC IRELAND LTD (IE) 2022-03-16 EP disclosed
US-11174258-B2 Benzimidazolo[1,2-a]benzimidazole derivatives for organic light emitting diodes IDEMITSU KOSAN CO., LTD. (JP) 2021-11-16 US disclosed
US-8362246-B2 Bispyrimidines for electronic applications BASF SE (DE) 2013-01-29 US disclosed
US-20120241681-A1 4H-Imidazo[1,2-a]imidazoles for Electronic Applications BASF SE (DE) 2012-09-27 US disclosed
US-8241764-B2 OLED display with extended lifetime BASF AKTIENGESELLSCHAFT (DE) 2012-08-14 US disclosed
US-20120149904-A1 BISPYRIMIDINES FOR ELECTRONIC APPLICATIONS BASF SE (DE) 2012-06-14 US disclosed
US-20120095222-A1 PHENANTHRO[9, 10-B]FURANS FOR ELECTRONIC APPLICATIONS BASF SE (DE) 2012-04-19 US disclosed
US-20120012821-A1 SILYL- AND HETEROATOM-SUBSTITUTED COMPOUNDS SELECTED FROM CARBAZOLES, DIBENZOFURANS, DIBENZOTHIOPHENES AND DIBENZOPHOSPHOLES, AND USE THEREOF IN ORGANIC ELECTRONICS BASF SE (DE) 2012-01-19 US disclosed
US-20110309346-A1 ORGANIC ELECTRONIC DEVICES COMPRISING A LAYER COMPRISING AT LEAST ONE METAL ORGANIC COMPOUND AND AT LEAST ONE METAL OXIDE BASF SE (DE) 2011-12-22 US disclosed
US-20110266528-A1 SUBSTITUTED CARBAZOLE DERIVATIVES AND USE THEREOF IN ORGANIC ELECTRONICS BASF SE (DE) 2011-11-03 US disclosed
US-20110198578-A1 SILOLES SUBSTITUTED BY FUSED RING SYSTEMS AND USE THEREOF IN ORGANIC ELECTRONICS OSRAM OPTO SEMICONDUCTORS GMBH (DE) 2011-08-18 US disclosed
US-20090278119-A1 OLED DISPLAY WITH EXTENDED LIFETIME BASF SE (DE) 2009-11-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (14 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11450812-B2 4H-imidazo[1,2-a]imidazoles for electronic applications PAH, NISCH, KCNH1 ALDH1A1 405/4885HPGD 486/4885NPC1 3851/4885
US-20120241681-A1 4H-Imidazo[1,2-a]imidazoles for Electronic Applications EIF4A1, ITPR2, ITPR1 ALDH1A1 355/4885HPGD 1129/4885NPC1 4473/4885
US-20120149904-A1 BISPYRIMIDINES FOR ELECTRONIC APPLICATIONS DPYD, TYMP, TYMS ALDH1A1 717/4885HPGD 1085/4885NPC1 4490/4885
US-12622170-B2 Fluorescent organic light emitting elements having high efficiency TEAD1, EEF1D, TEAD2 ALDH1A1 366/4885HPGD 2542/4885NPC1 2337/4885
US-20110198578-A1 SILOLES SUBSTITUTED BY FUSED RING SYSTEMS AND USE THEREOF IN ORGANIC ELECTRONICS HLCS, LAGE3, SUMO3 ALDH1A1 1138/4885HPGD 4082/4885NPC1 3771/4885
US-12538704-B2 4H-imidazo[1,2-a]imidazoles for electronic applications RIF1, NR2E1, NR3C1 ALDH1A1 680/4885HPGD 2024/4885NPC1 3180/4885
US-20230380277-A1 Fluorescent Organic Light Emitting Elements Having High Efficiency TEAD1, TEAD2, TEAD4 ALDH1A1 380/4885HPGD 3855/4885NPC1 2870/4885
US-11706978-B2 Fluorescent organic light emitting elements having high efficiency TEAD1, TEAD2, TEAD4 ALDH1A1 380/4885HPGD 3855/4885NPC1 2870/4885
US-20230090208-A1 4H-Imidazo[1,2-a]imidazoles for Electronic Applications PAH, NISCH, KCNH1 ALDH1A1 405/4885HPGD 486/4885NPC1 3851/4885
US-20120095222-A1 PHENANTHRO[9, 10-B]FURANS FOR ELECTRONIC APPLICATIONS P2RY10, P2RY11, P2RY12 ALDH1A1 1910/4885HPGD 1013/4885NPC1 4451/4885
US-11174258-B2 Benzimidazolo[1,2-a]benzimidazole derivatives for organic light emitting diodes KCNH2, KCNH3, KCNJ2 ALDH1A1 397/4885HPGD 4006/4885NPC1 3664/4885
US-11744152-B2 Benzimidazo[1,2-a]benzimidazole derivatives for electronic applications PAICS, EIF4A1, ECI1 ALDH1A1 122/4885HPGD 3271/4885NPC1 4384/4885
US-20110266528-A1 SUBSTITUTED CARBAZOLE DERIVATIVES AND USE THEREOF IN ORGANIC ELECTRONICS NR2E3, CHRNA5, CHRNA4 ALDH1A1 2923/4885HPGD 3989/4885NPC1 4492/4885
US-20120012821-A1 SILYL- AND HETEROATOM-SUBSTITUTED COMPOUNDS SELECTED FROM CARBAZOLES, DIBENZOFURANS, DIBENZOTHIOPHENES AND DIBENZOPHOSPHOLES, AND USE THEREOF IN ORGANIC ELECTRONICS DDT, CDKL1, CDK2 ALDH1A1 750/4885HPGD 3166/4885NPC1 4516/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.