Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | JAK2 | O60674 | 3/20 | 0.48 |
| ▸ | CLK2 | P49760 | 2/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.47 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.47 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.47 |
| ▸ | CLK1 | P49759 | 1/20 | 0.47 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.47 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.47 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.45 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.45 |
| ▸ | ACLY | P53396 | 1/20 | 0.45 |
| ▸ | PHGDH | O43175 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | JAK1 | P23458 | 2/20 | 0.43 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7567851 | 0.91 | PIK3CD (0.45) | NPC1RAB9AJAK2CLK2DYRK1A | |
| SCHEMBL7533688 | 0.79 | PABPC1 (0.56) | NPC1RAB9AALDH1A1LMNAMAPT | |
| SCHEMBL7534407 | 0.77 | LMNA (0.56) | NPC1RAB9AACLYALDH1A1LMNA | |
| SCHEMBL7566310 | 0.76 | GRM4 (0.41) | ACLYPHGDHALDH1A1LMNAMAPT | |
| SCHEMBL7534349 | 0.74 | ACLY (0.53) | RAB9AACLYALDH1A1LMNAMAPT | |
| SCHEMBL7539025 | 0.73 | MEN1 (0.62) | RAB9AACLYALDH1A1LMNAMAPT | |
| SCHEMBL7531704 | 0.73 | ALDH1A1 (0.57) | JAK2ACLYALDH1A1LMNAMAPT | |
| SCHEMBL7533710 | 0.72 | CYP3A4 (0.70) | ALDH1A1LMNAMAPTRXFP1 | |
| SCHEMBL1460717 | 0.72 | ALDH1A1 (0.80) | NPC1RAB9AJAK2PIK3CDROCK2 | |
| SCHEMBL7537204 | 0.72 | MAPT (0.51) | NPC1RAB9AACLYALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | disclosed |