Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 known ✓ | P00915 | 2/20 | 0.33 |
| ▸ | CA2 known ✓ | P00918 | 2/20 | 0.33 |
| ▸ | CA12 known ✓ | O43570 | 1/20 | 0.33 |
| ▸ | CA4 known ✓ | P22748 | 1/20 | 0.33 |
| ▸ | ADORA2A known ✓ | P29274 | 1/20 | 0.31 |
| ▸ | P2RY12 known ✓ | Q9H244 | 1/20 | 0.30 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RAD51 | Q06609 | 3/20 | 0.33 |
| ▸ | CA9 | Q16790 | 3/20 | 0.33 |
| ▸ | CA7 | P43166 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | PTPRC | P08575 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29512263 | 0.89 | RAD51 (0.40) | TTRGAARAD51CA9CA1 | |
| SCHEMBL757243 | 0.81 | TTR (0.41) | TTRGAACA9CA1CA2 | |
| SCHEMBL28404290 | 0.79 | TTR (0.42) | TTRGAACA9CA1CA2 | |
| SCHEMBL38675 | 0.74 | TTR (0.44) | TTRGAACA9CA1CA2 | |
| SCHEMBL7549672 | 0.74 | TTR (0.44) | TTRGAACA9CA1CA2 | |
| SCHEMBL38340 | 0.74 | CYP3A4 (0.53) | GAANFE2L2CYP3A4ALOX15CASP1 | |
| SCHEMBL65321 | 0.74 | CYP3A4 (0.53) | GAANFE2L2CYP3A4ALOX15CASP1 | |
| SCHEMBL3765477 | 0.74 | CYP3A4 (0.53) | GAANFE2L2CYP3A4ALOX15CASP1 | |
| SCHEMBL11656743 | 0.73 | TTR (0.43) | TTRGAACA9CA1CA2 | |
| SCHEMBL11287552 | 0.72 | CYP3A4 (0.50) | GAANFE2L2CYP3A4ALOX15CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0626374-B1 | A diaminostilbene series compound and a method for forming an image using the same | FUJI PHOTO FILM CO LTD (JP) | 2002-08-07 | — | — | EP | disclosed |
| EP-0631185-B1 | Method for continuously processing silver halide color photosensitive material | FUJI PHOTO FILM CO LTD (JP) | 1997-01-02 | — | — | EP | disclosed |
| US-5395742-A | IMAGEWISE EXPOSURE OF A PHOTOGRAPHIC MATERIAL TO LIGHT | FUJI PHOTO FILM CO., LTD. (JP) | 1995-03-07 | — | — | US | disclosed |
| US-5391467-A | Covering surface of color developer replenisher with layer of floating liquid; inhibiting precipitation | FUJI PHOTO FILM CO., LTD. (JP) | 1995-02-21 | — | — | US | disclosed |
| EP-0631185-A1 | Method for continuously processing silver halide color photosensitive material | Fuji Photo Film Co., Ltd. (JP) | 1994-12-28 | — | — | EP | disclosed |
| EP-0626374-A2 | A diaminostilbene series compound and a method for forming an image using the same | FUJI PHOTO FILM CO., LTD. (JP) | 1994-11-30 | — | — | EP | disclosed |