Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | NQO2 | P16083 | 6/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 6/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.38 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | METAP1 | P53582 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7248408 | 1.00 | KDM4E (0.49) | KDM4EGAALMNANQO2MTNR1A | |
| SCHEMBL7690123 | 0.78 | CA1 (0.43) | KDM4EGAALMNANQO2MTNR1A | |
| SCHEMBL7248144 | 0.78 | CA1 (0.43) | KDM4EGAALMNANQO2MTNR1A | |
| SCHEMBL7254509 | 0.74 | LMNA (0.43) | KDM4EGAALMNANQO2MTNR1A | |
| SCHEMBL7449552 | 0.74 | KDM4E (0.57) | KDM4EGAALMNANQO2MTNR1A | |
| SCHEMBL7254514 | 0.74 | LMNA (0.43) | KDM4EGAALMNANQO2MTNR1A | |
| SCHEMBL605776 | 0.74 | ACHE (0.52) | KDM4EGAALMNAMTNR1AMTNR1B | |
| SCHEMBL29979580 | 0.73 | ACHE (0.69) | MAPTL3MBTL1ACHEALDH1A1METAP1 | |
| SCHEMBL19553678 | 0.73 | ACHE (0.69) | MAPTL3MBTL1ACHEALDH1A1METAP1 | |
| SCHEMBL626213 | 0.71 | ACHE (0.58) | GAALMNAMTNR1AMTNR1BACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020151750-A1 | Process to prepare (2S)-2-(dipropylamino)-6-ethoxy-2,3-dihydro-1H-indene-5-carboxamide | CHEN JIONG JACK (US) | 2002-10-17 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020151750-A1 | Process to prepare (2S)-2-(dipropylamino)-6-ethoxy-2,3-dihydro-1H-indene-5-carboxamide | QDPR, DHPS, IMPDH2 | KDM4E 1000/4885GAA 1986/4885LMNA 2272/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.