Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NRP1 | O14786 | 6/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SLC10A6 | Q3KNW5 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7531331 | 0.69 | DHODH (0.55) | ACLYGAALMNAHPGDTSHR | |
| SCHEMBL7534407 | 0.69 | LMNA (0.56) | ACLYGAALMNAHPGDTSHR | |
| SCHEMBL532975 | 0.69 | ACLY (0.69) | ACLYGAALMNAHPGDTSHR | |
| SCHEMBL7531704 | 0.69 | ALDH1A1 (0.57) | ACLYLMNAHPGDTSHRKMT2A | |
| SCHEMBL7531142 | 0.69 | POLB (0.59) | GAALMNAHPGDTSHRKMT2A | |
| SCHEMBL7537945 | 0.69 | HPGD (0.67) | LMNAHPGDTSHRKMT2AMEN1 | |
| SCHEMBL7568445 | 0.69 | MEN1 (0.53) | KMT2AMEN1ALDH1A1MAPTGRM4 | |
| SCHEMBL7539025 | 0.69 | MEN1 (0.62) | ACLYLMNATSHRKMT2AMEN1 | |
| SCHEMBL7537204 | 0.68 | MAPT (0.51) | ACLYKMT2AMEN1ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL533067 | 0.68 | ACLY (0.68) | ACLYGAALMNAHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | disclosed |