SCHEMBL7570157

SCHEMBL7570157

[Na+].[O-]C(=S)c1ccco1

nearest known ligand 0.00

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3417259 0.76
SCHEMBL29485076 0.76 CES2 (0.62)
SCHEMBL3084123 0.75
SCHEMBL3085514 0.75
Hydrochloric Acid SCHEMBL18189710 0.73 CES2 (0.52)
SCHEMBL15294309 0.73
Hydrochloric Acid SCHEMBL28192420 0.73
SCHEMBL10766206 0.73
SCHEMBL2898916 0.73
SCHEMBL31486415 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119751389-A Preparation method of ethyl acetate solution of 2-furanmethyl thiol acid 山东中再生生物科技有限公司 2025-04-04 CN disclosed
US-6476220-B2 NUCLEOPHILIC DISPLACEMENT OF THE ACETOXY OF 7-AMINOCEPHALOSPORANIC ACID BY 2-THIOFUROIC ACID IN PRESENCE OF BORON TRIFLUORIDE IN A SOLVENT OR A MIXTURE OF SOLVENTS TO PREPARE CEPHALOSPORIN COMPOUND AUROBINDO PHARMA LIMITED (IN) 2002-11-05 US disclosed
US-20020065412-A1 Cephalosporin compound and a process for its preparation AUROBINDO PHARMA LIMITED (IN) 2002-05-30 US disclosed
US-4378314-A FOR PENICILLINS AND CEPHALOSPORINS BRISTOL MYERS COMPANY (US) 1983-03-29 US disclosed
US-4272437-A PENICILLINS BRISTOL-MYERS COMPANY (US) 1981-06-09 US disclosed