Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC26A6 | Q9BXS9 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 2/20 | 0.32 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.32 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6765 | 0.91 | BRD4 (0.33) | SLC26A6LMNAALOX5GAAMAOB | |
| SCHEMBL7297 | 0.91 | SCD5 (0.35) | SLC26A6LMNANPSR1TSHRTDP1 | |
| SCHEMBL11897090 | 0.90 | HDAC1 (0.36) | LMNANPSR1TDP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL2284 | 0.88 | NPSR1 (0.43) | SLC26A6LMNANPSR1TSHRTDP1 | |
| SCHEMBL6445 | 0.86 | CHRM1 (0.36) | SLC26A6LMNANPSR1TSHRPOLB | |
| SCHEMBL8174 | 0.86 | MAOB (0.41) | SLC26A6LMNAHTTALOX5ALOX5AP | |
| SCHEMBL7632 | 0.85 | KMT2A (0.38) | TSHRTDP1POLBHTTGAA | |
| SCHEMBL7532 | 0.85 | ALOX5 (0.35) | LMNANPSR1TDP1POLBHTT | |
| SCHEMBL2292 | 0.84 | CYP2C9 (0.42) | LMNANPSR1TSHRTDP1ALOX5 | |
| SCHEMBL6153 | 0.83 | GAA (0.36) | SLC26A6ALOX5ALOX5APGAABRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2483252-A2 | COMPOUNDS AS LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | Amira Pharmaceuticals, Inc. (US) | 2012-08-08 | — | — | EP | disclosed |
| WO-2011041694-A2 | COMPOUNDS AS LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | AMIRA PHARMACEUTICALS, INC. (US) | 2011-04-07 | — | — | WO | disclosed |