Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG known ✓ | P37231 | 6/20 | 0.48 |
| ▸ | PDE4A known ✓ | P27815 | 1/20 | 0.48 |
| ▸ | PDE3A known ✓ | Q14432 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 4/20 | 0.56 |
| ▸ | CES1 | P23141 | 4/20 | 0.56 |
| ▸ | FABP3 | P05413 | 4/20 | 0.50 |
| ▸ | PPARD | Q03181 | 6/20 | 0.48 |
| ▸ | PPARA | Q07869 | 6/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TLR2 | O60603 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | FABP4 | P15090 | 2/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.48 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.48 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29062638 | 1.00 | CES2 (0.56) | CES2CES1FABP3PPARGPPARD | |
| SCHEMBL10762301 | 1.00 | CES2 (0.56) | CES2CES1FABP3PPARGPPARD | |
| SCHEMBL18204921 | 0.96 | CES2 (0.56) | CES2CES1FABP3PPARGPPARD | |
| SCHEMBL8973505 | 0.96 | CES2 (0.56) | CES2CES1FABP3PPARGPPARD | |
| SCHEMBL18204916 | 0.96 | CES2 (0.56) | CES2CES1FABP3PPARGPPARD | |
| Zinc Ion SCHEMBL8745953 | 0.96 | CES2 (0.56) | CES2CES1FABP3PPARGPPARD | |
| Zinc Ion SCHEMBL18204925 | 0.96 | CES2 (0.56) | CES2CES1FABP3PPARGPPARD | |
| SCHEMBL18204911 | 0.96 | CES2 (0.56) | CES2CES1FABP3PPARGPPARD | |
| Potassium Ion SCHEMBL4019143 | 0.96 | CES2 (0.56) | CES2CES1FABP3PPARGPPARD | |
| SCHEMBL18204917 | 0.93 | CES2 (0.54) | CES2CES1FABP3PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116869839-A | Polyglycerol ester emulsion, preparation method and application | 上海汇翔生化科技有限公司 | 2023-10-13 | — | — | CN | claimed |
| CN-116869839-A | Polyglycerol ester emulsion, preparation method and application | 上海汇翔生化科技有限公司 | 2023-10-13 | — | — | CN | disclosed |
| CN-116725906-A | Face cream containing sweet wormwood volatile oil and application thereof | 上海昆药生物科技有限公司 | 2023-09-12 | — | — | CN | disclosed |
| EP-1250360-A2 | METHOD FOR MAKING HYDROPHOBICALLY ASSOCIATIVE POLYMERS, METHODS OF USE AND COMPOSITIONS | Hercules Incorporated (US) | 2002-10-23 | — | — | EP | disclosed |
| WO-2001040318-A2 | METHOD FOR MAKING HYDROPHOBICALLY ASSOCIATIVE POLYMERS, METHODS OF USE AND COMPOSITIONS | HERCULES INCORPORATED (US) | 2001-06-07 | — | — | WO | disclosed |