Sugi Predict

Sugi Predict / Compounds / SCHEMBL759009

SCHEMBL759009

SCHEMBL759009

C=CCN(O)[C@@H](CCC(N)=O)C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ BLM P54132 2/20 0.41
▸ KMT2A Q03164 2/20 0.41
▸ ALOX15 P16050 1/20 0.41
▸ PMP22 Q01453 1/20 0.41
▸ ALDH1A1 P00352 1/20 0.32
▸ SLC6A2 P23975 1/20 0.32
▸ SLC6A4 P31645 1/20 0.32
▸ SLC6A3 Q01959 1/20 0.32
▸ MEN1 O00255 1/20 0.32
▸ CYP2D6 P10635 1/20 0.32
▸ TSHR P16473 1/20 0.32
▸ NFKB1 P19838 1/20 0.32
▸ CYP2C19 P33261 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1843778 1.00 BLM (0.41) BLMKMT2AALOX15PMP22ALDH1A1
SCHEMBL10355086 0.86 SLC6A2 (0.41) BLMKMT2AALDH1A1SLC6A2SLC6A4
SCHEMBL28959981 0.84 BLM (0.42) BLMKMT2AALOX15PMP22ALDH1A1
SCHEMBL28959979 0.84 BLM (0.42) BLMKMT2AALOX15PMP22ALDH1A1
SCHEMBL757318 0.82 GRIK1 (0.31) ALDH1A1
SCHEMBL5696080 0.81 BLM (0.40) BLMKMT2AALOX15PMP22ALDH1A1
SCHEMBL8658486 0.81 BLM (0.40) BLMKMT2AALOX15PMP22ALDH1A1
SCHEMBL5696078 0.81 BLM (0.40) BLMKMT2AALOX15PMP22ALDH1A1
SCHEMBL3335954 0.77 ALOX15 (0.45) BLMKMT2AALOX15PMP22SLC6A3
SCHEMBL1221384 0.77 ALOX15 (0.45) BLMKMT2AALOX15PMP22SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 331 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150099808-A1 AMPHIPHILIC COPOLYMERS AND COMPOSITIONS CONTAINING SUCH POLYMERS NIRVANA'S TREE HOUSE B.V. (NL) 2015-04-09 — — US claimed
JP-2011529100-A — — 2011-12-01 — — JP claimed
US-20110182813-A1 AMPHIPHILIC COPOLYMERS AND COMPOSITIONS CONTAINING SUCH POLYMERS NIRVANA'S TREE HOUSE B.V. (NL) 2011-07-28 — — US claimed
EP-2317990-A2 MICROPARTICULATE ORAL DRUG FORM USEFUL FOR THE MODIFIED RELEASE OF NANOPARTICLES Flamel Technologies (FR) 2011-05-11 — — EP claimed
EP-2195366-A1 AMPHIPHILIC COPOLYMERS AND COMPOSITIONS CONTAINING SUCH POLYMERS Nirvana's Tree House B.v. (NL) 2010-06-16 — — EP claimed
WO-2010012940-A2 MICROPARTICULATE ORAL DRUG FORM USEFUL FOR THE MODIFIED RELEASE OF NANOPARTICLES FLAMEL TECHNOLOGIES (FR) 2010-02-04 — — WO claimed
US-20100021549-A1 Microparticle oral form useful for the modified release of nanoparticles FLAMEL TECHNOLOGIES, S.A. (FR) 2010-01-28 — — US claimed
WO-2009037313-A1 AMPHIPHILIC COPOLYMERS AND COMPOSITIONS CONTAINING SUCH POLYMERS NIRVANA'S TREE HOUSE B.V. (NL) 2009-03-26 — — WO claimed
US-4116949-A WATER-SOLUBLE, PHYSIOLOGICALLY ACTIVE, SYNTHETIC COPOLYPEPTIDES THE REAGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1978-09-26 — — US claimed
JP-62258703-A — — None — — JP disclosed
US-20240116895-A1 ESTER SUBSTITUTED ION CHANNEL BLOCKERS AND METHODS FOR USE NOCION THERAPEUTICS INC (US) 2024-04-11 — — US disclosed
US-20240100032-A1 Charged Ion Channel Blockers and Methods for Use NOCION THERAPEUTICS INC (US) 2024-03-28 — — US disclosed
EP-3485881-B1 PERMANENTLY CHARGED SODIUM AND CALCIUM CHANNEL BLOCKERS AS ANTI-INFLAMMATORY AGENTS HARVARD COLLEGE (US) 2024-03-13 — — EP disclosed
US-20240076305-A1 Phosphonium Ion Channel Blockers and Methods for Use NOCION THERAPEUTICS INC (US) 2024-03-07 — — US disclosed
EP-0245820-A2 Biodegradable microspheres as a carrier for macromolecules The University of Kentucky Research Foundation (US) 1987-11-19 — — EP disclosed
JP-S62258703-A MEMBRANE FOR SEPARATING SACCHARIDE AGENCY OF IND SCIENCE & TECHNOL 1987-11-11 — — JP disclosed
EP-0167828-A1 A man-made skin composed of two layers:Collagen and a poly-alpha-amino acid KOKEN CO. LTD. (JP) 1986-01-15 — — EP disclosed
EP-0164569-A2 A medicine-releasing agent KOKEN CO. LTD. (JP) 1985-12-18 — — EP disclosed
US-4125519-A Polypeptides containing 3,4-dihydroxyphenylalanine GOODMAN MURRAY 1978-11-14 — — US disclosed
US-4116949-A WATER-SOLUBLE, PHYSIOLOGICALLY ACTIVE, SYNTHETIC COPOLYPEPTIDES THE REAGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1978-09-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100021549-A1 Microparticle oral form useful for the modified release of nanoparticles MC1R, PTMS, MRPL37 BLM 4391/4885KMT2A 4857/4885ALOX15 1826/4885
US-20110182813-A1 AMPHIPHILIC COPOLYMERS AND COMPOSITIONS CONTAINING SUCH POLYMERS GLUL, ASNS, ARGLU1 BLM 2609/4885KMT2A 1839/4885ALOX15 3313/4885
US-20150099808-A1 AMPHIPHILIC COPOLYMERS AND COMPOSITIONS CONTAINING SUCH POLYMERS GLUL, ASNS, ARGLU1 BLM 2609/4885KMT2A 1839/4885ALOX15 3313/4885
US-20240100032-A1 Charged Ion Channel Blockers and Methods for Use TRPV1, ASIC1, TRPA1 BLM 2975/4885KMT2A 3122/4885ALOX15 1142/4885
US-20240116895-A1 ESTER SUBSTITUTED ION CHANNEL BLOCKERS AND METHODS FOR USE TRPV1, TRPA1, TRPV2 BLM 4244/4885KMT2A 2763/4885ALOX15 287/4885
US-20240076305-A1 Phosphonium Ion Channel Blockers and Methods for Use TRPV1, TRPV5, TRPA1 BLM 4437/4885KMT2A 3568/4885ALOX15 517/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.