Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.53 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.52 |
| ▸ | PTGES2 | Q9H7Z7 | 4/20 | 0.50 |
| ▸ | EDNRB | P24530 | 2/20 | 0.50 |
| ▸ | EDNRA | P25101 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | CCR2 | P41597 | 3/20 | 0.48 |
| ▸ | ACLY | P53396 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7591197 | 0.87 | PTGES2 (0.59) | SLC40A1HSD11B1PTGES2EDNRBEDNRA | |
| SCHEMBL7588152 | 0.84 | SLC40A1 (0.59) | SLC40A1HSD11B1PTGES2EDNRBEDNRA | |
| SCHEMBL7594250 | 0.84 | SLC40A1 (0.66) | SLC40A1HSD11B1PTGES2EDNRBEDNRA | |
| SCHEMBL7572722 | 0.81 | ALDH1A1 (0.56) | SLC40A1HSD11B1EDNRBEDNRAPKM | |
| SCHEMBL7578810 | 0.81 | SLC40A1 (0.64) | SLC40A1HSD11B1PTGES2EDNRBEDNRA | |
| SCHEMBL7596336 | 0.80 | HSD11B1 (0.55) | SLC40A1HSD11B1PTGES2EDNRBEDNRA | |
| SCHEMBL29335255 | 0.78 | SLC40A1 (0.51) | SLC40A1HSD11B1PTGES2EDNRBEDNRA | |
| SCHEMBL7573034 | 0.78 | ACLY (0.53) | SLC40A1HSD11B1EDNRBEDNRAACLY | |
| SCHEMBL7591248 | 0.76 | HSD11B1 (0.63) | SLC40A1HSD11B1PTGES2EDNRBEDNRA | |
| SCHEMBL7572428 | 0.75 | ALDH1A1 (0.54) | SLC40A1HSD11B1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |