SCHEMBL7598968

SCHEMBL7598968

Nc1cc(S(=O)(=O)O)cc2cc(S(=O)(=O)[O-])cc(O)c12.[Na+]

nearest known ligand 0.81

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NT5E P21589 2/20 0.81
PTPN1 P18031 3/20 0.67
ALDH1A1 P00352 3/20 0.53
HSD17B10 Q99714 3/20 0.53
CASP6 P55212 3/20 0.51
CYP2C9 P11712 2/20 0.51
CYP2C19 P33261 2/20 0.51
DUSP5 Q16690 1/20 0.50
CYP1A2 P05177 2/20 0.46
NSD2 O96028 2/20 0.45
DUSP3 P51452 1/20 0.45
PTPN5 P54829 1/20 0.45
PTPN11 Q06124 1/20 0.45
APEX1 P27695 3/20 0.44
L3MBTL1 Q9Y468 2/20 0.43
GAA P10253 2/20 0.43
PLCG1 P19174 1/20 0.43
DNMT1 P26358 1/20 0.43
USP2 O75604 1/20 0.42
ATM Q13315 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29379230 1.00 NT5E (0.81) NT5EPTPN1ALDH1A1HSD17B10CASP6
SCHEMBL31202727 1.00 NT5E (0.81) NT5EPTPN1ALDH1A1HSD17B10CASP6
SCHEMBL564761 1.00 NT5E (0.81) NT5EPTPN1ALDH1A1HSD17B10CASP6
Water SCHEMBL30148471 0.98 NT5E (0.79) NT5EPTPN1ALDH1A1HSD17B10CASP6
SCHEMBL6840783 0.94 PTPN1 (0.76) NT5EPTPN1ALDH1A1HSD17B10CASP6
SCHEMBL29976911 0.94 PTPN1 (0.76) NT5EPTPN1ALDH1A1HSD17B10CASP6
SCHEMBL3100229 0.94 PTPN1 (0.76) NT5EPTPN1ALDH1A1HSD17B10CASP6
Water SCHEMBL12275539 0.92 PTPN1 (0.73) NT5EPTPN1ALDH1A1HSD17B10CASP6
SCHEMBL22730239 0.92 PTPN1 (0.73) NT5EPTPN1ALDH1A1HSD17B10CASP6
SCHEMBL150291 0.90 NT5E (1.00) NT5EPTPN1ALDH1A1HSD17B10CASP6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114539803-B Direct red/direct violet dye compound and preparation method and application thereof 广东省科学院测试分析研究所(中国广州分析测试中心) 2024-08-30 CN claimed
CN-114539803-A Direct red/direct violet dye compound and preparation method and application thereof 广东省科学院测试分析研究所(中国广州分析测试中心) 2022-05-27 CN claimed
CN-107602809-B High-solid-content aqueous polyurethane dispersion liquid based on aminocarboxylate and sulfamate simultaneously 温州大学 2020-05-22 CN claimed
CN-114539803-B Direct red/direct violet dye compound and preparation method and application thereof 广东省科学院测试分析研究所(中国广州分析测试中心) 2024-08-30 CN disclosed
CN-114539803-A Direct red/direct violet dye compound and preparation method and application thereof 广东省科学院测试分析研究所(中国广州分析测试中心) 2022-05-27 CN disclosed
CN-114032215-B Hybridoma cell strain secreting red 2G monoclonal antibody and application thereof 江南大学 2022-05-17 CN disclosed
CN-114032215-A Hybridoma cell strain secreting red 2G monoclonal antibody and application thereof 江南大学 2022-02-11 CN disclosed
US-11214702-B2 Black coloring composition STIERNON ROBERT ETS, SA (BE) 2022-01-04 US disclosed
US-20200385598-A1 BLACK COLORING COMPOSITION STIERNON ROBERT ETS, SA (BE) 2020-12-10 US disclosed
EP-3747964-A1 BLACK COLOURANT COMPOSITION Stiernon Robert ETS société anonyme (BE) 2020-12-09 EP disclosed
CN-107602809-B High-solid-content aqueous polyurethane dispersion liquid based on aminocarboxylate and sulfamate simultaneously 温州大学 2020-05-22 CN disclosed
US-4988805-A Naphtholazophenylazoaminonaphthol compounds and copper complexes thereof BAYER AKTIENGESELLSCHAFT (DE) 1991-01-29 US disclosed
US-4230852-A CELLULOSE, COTTON, ORANGE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1980-10-28 US disclosed
US-4229584-A Ureylenebis(anionic substituted phenylene carbonyl)imino naphthalene sulfonic acids and naphthalene carboxylic acids and their salts AMERICAN CYANAMID COMPANY (US) 1980-10-21 US disclosed
US-4177209-A COMPLEMENT INHIBITORS AMERICAN CYANAMID COMPANY (US) 1979-12-04 US disclosed
US-4148790-A FOR CELLULOSIC FIBERS SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1979-04-10 US disclosed
US-4129590-A INHIBITORS OF THE COMPLEMENT SYSTEM AMERICAN CYANAMID COMPANY (US) 1978-12-12 US disclosed
US-4103028-A SUBSTITUTED HYDROXY NAPHTHALENEDISULFONIC ACIDS AMERICAN CYANAMID COMPANY (US) 1978-07-25 US disclosed
US-4046805-A Substituted-hydroxy-naphthalenedisulfonic acid compounds AMERICAN CYANAMID COMPANY (US) 1977-09-06 US disclosed
US-4038267-A TRIAZINE REACTIVE DYES SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1977-07-26 US disclosed