SCHEMBL759946

SCHEMBL759946

Nc1ccc(S(=O)(=O)Cl)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.62
HTR6 P50406 3/20 0.62
LMNA P02545 3/20 0.62
MPO P05164 1/20 0.62
CYP3A4 P08684 1/20 0.62
CYP2C9 P11712 1/20 0.62
CA2 P00918 4/20 0.59
CA9 Q16790 4/20 0.59
CA1 P00915 3/20 0.59
CA12 O43570 3/20 0.59
TDP1 Q9NUW8 2/20 0.59
CA14 Q9ULX7 2/20 0.59
AGO2 Q9UKV8 2/20 0.59
USP2 O75604 1/20 0.59
CA4 P22748 1/20 0.59
CA6 P23280 1/20 0.59
CA5A P35218 1/20 0.59
CA7 P43166 1/20 0.59
CA13 Q8N1Q1 1/20 0.59
CA5B Q9Y2D0 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL2235344 0.97 TSHR (0.59) TSHRHTR6LMNAMPOCYP3A4
Acetaldehyde SCHEMBL4349619 0.89 TSHR (0.50) TSHRHTR6LMNAMPOCYP3A4
SCHEMBL14610271 0.87 GFER (0.58) TSHRHTR6LMNAMPOCYP3A4
Dapsone SCHEMBL11375057 0.87 HTR6 (0.67) TSHRHTR6LMNAMPOCYP3A4
SCHEMBL651902 0.85 ALDH1A1 (0.71) TSHRHTR6LMNAMPOCYP3A4
Sulfanilamide SCHEMBL29080914 0.79 CA2 (0.85) TSHRHTR6LMNAMPOCYP3A4
SCHEMBL2367293 0.78 CA2 (0.64) TSHRCA2CA9CA1CA12
SCHEMBL27446604 0.77 TSHR (0.86) TSHRHTR6LMNAMPOCYP3A4
SCHEMBL948147 0.77 ALDH1A1 (0.46) TSHRHTR6LMNAMPOCYP3A4
SCHEMBL324893 0.77 HTR6 (1.00) TSHRHTR6LMNAMPOCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 238 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250107976-A1 COMPOSITIONS AND METHODS FOR TREATING HAIR L'OREAL (FR) 2025-04-03 US claimed
WO-2025072691-A1 COMPOSITIONS AND METHODS FOR TREATING HAIR HART TAYLOR (US) 2025-04-03 WO claimed
CN-119241399-A Benzenesulfonyl compound taking AR/AR-V7 double protein as target point and preparation method and application thereof 上海应用技术大学 2025-01-03 CN claimed
WO-2024205303-A1 NOVEL AMIDE-BASED COMPOUND AND COMPOSITION COMPRISING SAME (주)아모레퍼시픽 2024-10-03 WO claimed
CN-118028896-A Production method of alkaline electrolyzed water hydrogen production diaphragm 湖北氢益氢能科技有限公司 2024-05-14 CN claimed
CN-117126695-B Preparation method of degradable lubricating oil 广州市蔚森节能科技有限公司 2024-01-30 CN claimed
CN-117126695-A Preparation method of degradable lubricating oil 广州市蔚森节能科技有限公司 2023-11-28 CN claimed
US-20230301892-A1 COMPOSITIONS AND METHODS FOR ELONGATING CURLY HAIR L'OREAL (FR) 2023-09-28 US claimed
WO-2023154471-A2 COMPOSITIONS AND METHODS FOR STYLING HAIR LAGA STEPHANIE (US) 2023-08-17 WO claimed
US-20230248629-A1 COMPOSITIONS AND METHODS FOR STYLING HAIR L'OREAL (FR) 2023-08-10 US claimed
US-20190201309-A1 COMPOSITIONS FOR ALTERING THE COLOR OF HAIR L'OREAL (FR) 2019-07-04 US claimed
US-9556342-B2 Zwitterionic lignin derivatives EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2017-01-31 US claimed
CN-104678028-A Pretreatment and detection method for biogen amine neurotransmitter and detection kit INST PHARM & TOXICOLOGY AMMS 2015-06-03 CN claimed
US-20150135989-A1 ZWITTERIONIC LIGNIN DERIVATIVES CRESTLINE DIRECT FINANCE, L.P. 2015-05-21 US claimed
EP-2528923-B1 PROCESS FOR THE PREPARATION OF DARUNAVIR AND DARUNAVIR INTERMEDIATES MAPI PHARMA LTD (IL) 2014-07-30 EP claimed
EP-2528923-A1 PROCESS FOR THE PREPARATION OF DARUNAVIR AND DARUNAVIR INTERMEDIATES Mapi Pharma Limited (IL) 2012-12-05 EP claimed
CN-102725295-A Process for the preparation of darunavir and darunavir intermediates MAPI PHARMA HK LTD 2012-10-10 CN claimed
WO-2011092687-A1 PROCESS FOR THE PREPARATION OF DARUNAVIR AND DARUNAVIR INTERMEDIATES MAPI PHARMA HK LIMITED (CN) 2011-08-04 WO claimed
EP-2120555-A1 METHODS AND COMPOSITIONS FOR THE TREATMENT OF PAIN Heller, Adam (US) 2009-11-25 EP claimed
WO-2008094664-A1 METHODS AND COMPOSITIONS FOR THE TREATMENT OF PAIN HELLER ADAM (US) 2008-08-07 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230248629-A1 COMPOSITIONS AND METHODS FOR STYLING HAIR DPM1, NACA, FUT6 TSHR 4465/4885HTR6 720/4885LMNA 2855/4885
US-20190201309-A1 COMPOSITIONS FOR ALTERING THE COLOR OF HAIR TYR, SHH, AADAT TSHR 3883/4885HTR6 1440/4885LMNA 1513/4885
US-20230301892-A1 COMPOSITIONS AND METHODS FOR ELONGATING CURLY HAIR GLUL, NACA, SHH TSHR 4654/4885HTR6 1122/4885LMNA 2888/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.